Size-Exclusion Chromatography Analysis of Adeno-Associated Virus (AAV) Preparations Using a 450 Å Diol-Bonded BEH Column and Fluorescence Detection

Library Number:
APNT135047399
Part Number:
720006812EN
Author(s):
Stephan M. Koza, Weibin Chen
Source:
Waters
Content Type:
Application Notes
Content Subtype:
Application Notes
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Here we present optimized size-exclusion chromatography (SEC) methods that can separate soluble AAV self-associated forms and fragments under non-denaturing conditions for several CMV-GFP control AAV serotypes including AAV1, AAV2, AAV5, AAV6, AAV8, and AAV9.


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