Automated Quantitative Analysis of Antibody Drug Conjugates Using an Accurate Mass Screening Workflow in the UNIFI Scientific Information System

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Liuxi Chen, Steven Cubbedge, Ying Qing Yu, and Rose Lawler
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Application Notes
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This application note describes how to perform ADC peptide quantitation using the Accurate Mass Screening workflow in UNIFI and further demonstrates the capability of comparing the key product attributes of ADCs across samples through this automated workflow.

The Accurate Mass Screening workflow (quantitative tool) combined with UNIFI scientific library and Custom Field is a great addition to the traditional Peptide Mapping MSE workflow (qualitative tool) within the same UNIFI architecture to facilitate the challenges of ADC biotherapeutics research and development.

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