Transferring an HPLC Method for Related Substances from Different LC Platforms to an ACQUITY Arc System

Library Number:
APNT134875994
Part Number:
720005558EN
Author(s):
Margaret Maziarz and Mark Wrona
Source:
Waters
Content Type:
Application Notes
Content Subtype:
Application Notes
Related Products:
 
 
 
 

This application note presents the transfer of an HPLC method for related substances of metoclopramide HCl from different LC systems to an ACQUITY Arc System.

The ACQUITY Arc System successfully replicated the assay method for related substances of metoclopramide HCl run on an Agilent 1100 Series LC, Agilent 1260 Infinity Quaternary LC, and Alliance HPLC Systems. The ACQUITY QDa Detector coupled to an ACQUITY Arc System enabled quick peak identification using mass spectral data. Overall, the ACQUITY Arc System allows efficient method transfer from any LC platform, as well as flexible method optimization.


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