Chromatographic Methodologies: An Integral Component of the Budding Cannabis Industry
Fueled by recent revelations of the potential to treat many conditions with cannabinoid therapies, the cannabis industry is now becoming a well-organized, respectable industry. With this legitimization also comes regulation to ensure consumer safety. At the heart of this regulation are the chromatographic methods necessary to test cannabis products for potency and to confirm the absence of harmful contaminants:
- Supercritical fluid chromatography (SFC) facilitates analysis of the complex interactions and degradation pathways of the cannabinoids through the cultivation and manufacturing process. These analyses are critical for understanding manufacturing processes, patient dosing, and product shelf life.
- Gas chromatography (GC) is ideal for the identification of the phytochemical terpene constituents, which have been indicated in having therapeutic synergy with the cannabinoids.
- Headspace gas chromatography (HS-GC) can be used to identify the residual solvents that may result from the many extraction and processing methods.
- Liquid chromatography with mass spectrometric detection (LC–MS-MS) can play a vital role in pesticide testing.
- In addition, manufacturing processes can benefit from the use of preparative SFC for the isolation and purification of the individual cannabinoids for the preparation of custom formulations to target specific cannabinoid therapies.
This webinar surveys the use of these chromatographic methodologies and discuss their integral role in building a legitimate, regulated cannabis industry.
This webinar was hosted live by LCGC on June 12, 2015. Watch on-demand