Comprehensive Characterization of the N and O-Linked Glycosylation of a Recombinant Human EPO

Library Number:
APNT134855745
Part Number:
720005462EN
Author(s):
Matthew A. Lauber, Stephan M. Koza, and Erin E. Chambers
Source:
Waters
Content Type:
Application Notes
Content Subtype:
Application Notes
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This application note demonstrates the use of two facile strategies that can be used to detail both the N and O-linked glycosylation of recombinant, human epoetin (rhEPO), a molecule which has been perceived to be challenging to characterize due to its relatively complicated glycosylation. Collectively, these tools could be used to accelerate the development of new biosimilars.


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