OasisR PRiME HLB is a novel reversed phase solid phase extraction (SPE) sorbent
developed to enable simpler and faster SPE protocols, while at the same time
generating cleaner extracts than other sample preparation methods. With Oasis
PRiME HLB, a 3-step load-wash-elute SPE protocol eliminating conditioning and equilibration was successfully employed to extract 22 synthetic cannabinoids and metabolites from whole blood samples. Excellent analyte recoveries and modest matrix effects (ME) were achieved across the entire panel of compounds.