Screening Synthetic Adulterants from Herbal and Dietary Supplements (HDS) Using the Natural Products Application Solution with UNIFI

Library Number:
APNT134843348
Part Number:
720005396EN
Author(s):
Dhavalkumar Narendrabhai Patel, Lirui Qiao, Jimmy Yuk, and Kate Yu
Source:
Waters Corporation
Content Type:
Application Notes
Content Subtype:
Application Notes
Related Products:
 
 
 
 
 

In recent years, there has been a tremendous increase in the use of natural products in the form of herbal supplements for health benefits and therapeutic effects. Unfortunately, this rise in usage has also led to the increased chance of products being adulterated with synthetic compounds by unscrupulous manufacturers. There have been reports of severe to even fatal cases1 related to adulteration in herbal products. This has raised global concerns within the natural products community and with various regulatory authorities since it poses a significant risk to consumers.

Here, we demonstrate the utility of the Natural Products Application Solution with UNIFI Adulterant Screening Application and the Synthetic Adulterant Library with the analysis of a commercial herbal supplement product. This product is a herbal capsule sold by street vendors to alleviate back and joint pain (in rheumatoid arthritis). The label claim indicates that it contains various herbs such as Picrorhiza kurroa and Strychnos nux-vomica Linn. Using the Natural Products Application Solution with UNIFI Adulterant Screening Application, we were able to automatically detect the existence of any synthetic compounds, and then confirm the identified adulterants through an easy review process, to quickly draw a conclusion.

 


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