Increasing Sensitivity for Tof-MS Detection of Polychlorinated Biphenyls (PCBs) Using Tof MRM

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Lauren Mullin and Adam Ladak
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Application Notes
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Polychlorinated biphenyls (PCBs) are persistent organic pollutants which have been banned from production as a result of their observed accumulation in biota and the environment. Various levels of toxicity have also been associated with PCBs, in particular the 12 dioxin-like PCB congeners. In this technology brief, learn how Tof MRM enhances the analytical capabilities of high resolution mass spectrometry, affording lower limits of detection while maintaining the ability to collect information rich accurate mass full scan data. These benefits have been applied here to the analysis of PCBs, which requires instrumental sensitivity and selectivity for detection in complex environmental matrices.

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