The ACQUITY UPLC System coupled with an ACQUITY QDa Detector eliminates the titrimetric and flow injection techniques and provides simplistic analysis of the EDC•HCl raw material. System suitability and linearity of the method calculated using mass data were excellent. The new method provides improved confidence associated with sample confirmation and increased productivity.
Overall, the ACQUITY QDa Detector is a robust and simple-to-use mass detector that can be added as an orthogonal detection technique to UV detection. It provides accurate and reliable results, making this technology ideal for routine testing in the QC laboratory.