Robustness of ionKey/MS System in the Analysis of Pharmaceutical Compounds in Biological Fluids

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Paul D. Rainville and Catalin Doneanu
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Application Notes
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Application Notes
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Ultra High Sensitivity Bioanalysis

This work illustrates the robustness of the ionKey/MS System when analyzing complex biological samples produced by complex biological samples produced by common bioanalytical sample preparation techniques. We demonstrate the ionKey/MS System's robustness in the analysis of plasma samples prepared by crude protein precipitation (PPT), liquid-liquid extraction (LLE), and by immunoaffinity isolation followed by trypsin digestion (IA/TD).

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