Robustness of ionKey/MS System in the Analysis of Pharmaceutical Compounds in Biological Fluids

Library Number:
APNT134783313
Part Number:
720004953en
Author(s):
Paul D. Rainville and Catalin Doneanu
Source:
Waters
Content Type:
Application Notes
Content Subtype:
Application Notes
Related Products:
 
Ultra High Sensitivity Bioanalysis
 
 
 
 
 

This work illustrates the robustness of the ionKey/MS System when analyzing complex biological samples produced by complex biological samples produced by common bioanalytical sample preparation techniques. We demonstrate the ionKey/MS System's robustness in the analysis of plasma samples prepared by crude protein precipitation (PPT), liquid-liquid extraction (LLE), and by immunoaffinity isolation followed by trypsin digestion (IA/TD).


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