Transferring Compendial HPLC Methods to UPLC Technology for Routine Generic Drug Analysis

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Kenneth J. Fountain
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Application Notes
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UPLC Technology can provide tremendous benefits to routine testing of generic drug products, including increased sample throughput and decreased solvent consumption (including subsequent disposal). Analysis times can be reduced by 70 to 90%, and solvent consumption can be decreased by over 90%. This offers significant cost benefits associated with running more samples in less time, and can decrease the overall operating expenses in development and quality control laboratories. Most of all, it helps provide a competitive advantage to generic drug companies who leverage UPLC Technology to bring drugs to market faster and cheaper.

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