Alternate Selectivity for Bases in UltraPerformance Liquid Chromatography

Library Number:
APNT10075297
Part Number:
720002460en
Author(s):
Jane Xu, Kenneth J. Fountain, Eric S. Grumbach and Diane M. Diehl
Source:
LCGC Asia Pacific
Content Type:
Application Notes
Content Subtype:
Application Notes
Compounds:
aminopyrazine, pindolol, labetalol, quinine, verapamil, diltiazem, amitriptyline
Column:
10075298 ACQUITY UPLC HSS C18 SB 1.8 µm 2.1 x 50 mm 10075299 ACQUITY UPLC HSS T3 1.8 µm 2.1 x 50 mm 10075300 ACQUITY UPLC BEH Shield RP18 1.7 µm 2.1 x 50 mm
A non-endcapped C18 stationary phase bonded to a 1.8 µm high strength silica (HSS) particle substrate was developed to provide different selectivities in UltraPerformance Liquid Chromatography (UPLC technology) separations.  ACQUITY UPLC HSS C18 SB (Selectivity for Bases) columns provide alternate selectivity for bases under acidic conditions and provide an additional UPLC method development tool.

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