Determination of Common Beta-Agonist Residues in Meat Products by UPLC-MS/MS

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Yiping Ren, Jinchuan Yang
Waters, Zhejiang Provincial Center for Disease Prevention and Control
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Application Notes
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Application Notes
Related Products:
Xevo TQ-S

This application note describes the use of the ACQUITY UPLC System, coupled with the Xevo TQ-S Mass Spectrometer for the determination of three common beta agonist residues (clenbuterol, ractopamine, and salbutamol) in meat. Compared to the GB method, the sample run time has been shortened from 26 minutes to 7 minutes with UPLC; the sample extraction procedure and chromatographic conditions have been optimized; and additional MRM transitions and stable isotope international standards have been employed to improve the analysis. In addition, the ACQUITY UPLC HSS T3 1.8 μm Column was investigated during the actual meat product analysis.

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