Revolutionizing SPE with Otto SPEcialist: An Easy-to-Use, Software-Driven, Positive Pressure Manifold

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Kathryn Brennan, Jonathan P. Danaceau, Paula Orens
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Application Notes
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Technical Notes
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This work compares Waters Otto SPEcialist, a semi-automated positive pressure sample preparation device, to the Hamilton Microlab STAR, a fully automated, vacuum equipped system, for a previously validated solid-phase extraction (SPE) application. This broadly applicable method involves the use of the Otto Software technology which provides comparable recovery to a fully automated system, and accurate, reproducible quantification of controlled drugs from urine samples in support of research in forensic toxicology.

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