This technical note familiarizes the scientists with the aggressive solvent compatible APC System using a gradient elution for the analysis of non-polar and polar polymer additives in one chromatographic result.
Polymer manufacturers rely on the timely analytical characterization of their raw materials. One aspect of polymer analysis is the qualification and quantification of polymer additives.
Analysis using legacy chromatographic methods and instrumentation can be time-consuming and tell only part of the story. However, transferring legacy high performance liquid chromatography (HPLC) methods to a Waters™ ACQUITY™ Advanced Polymer Chromatography (APC™) System, with a Polymer Quaternary Solvent Manager (p-QSM) and an ACQUITY UPLC™ PDA (photodiode array) Detector, provides gradient elution of polymer additives using aggressive solvents like tetrahydrofuran (THF) quickly and without system modifications during installation.