Future-Proofing the QC Laboratory for UPLC While Enabling the Faithful Analysis of Legacy HPLC Methods

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Chris Henry, Mark Wrona, Richard Ladd, Andy Boughey
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This application note describes how AstraZeneca’s QC department in Macclesfield, UK has successfully transferred and run all their registered QC methods on an ACQUITY UPLC® H-Class System.

The Waters ACQUITY UPLC H-Class Systems’ success in transitioning legacy methods within the Quality Control environment of AstraZeneca exemplifies the instrument’s ability to offer a seamless alternative to existing HPLC platforms, while uniquely offering the option of true UPLC technology when desired.

AstraZeneca now successfully runs all registered QC methods on an ACQUITY UPLC H-Class System, with three high throughput products successfully transferred to UPLC and validated.

The success of the Waters ACQUITY UPLC H-Class System in the Quality Control department of AstraZeneca Macclesfield has led to a wider adoption of the system by AstraZeneca globally.

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