This application note presents the versatility of direct injection using the ACQUITY I-Class UPLC System with the Xevo TQ-S Mass Spectrometer for the analysis of diquat and paraquat in tap water and bottled water. The limit of detection in this study was 50 ppt, which is below the European Union Directive LOD of 100 ppt. The high sensitivity of Xevo TQ-S enabled excellent quantitation using a 100-μL injection without sample extraction or concentration prior injection. The recovery data showed good results with excellent RSD’s below 8% for both water samples.
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