UPLC/MS/MS Method for the Routine Quantification of Regulated and Non-Regulated Lipophilic Marine Biotoxins in Shellfish

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Arjen Gerssen, Mirjam D. Klijnstra, Simon Cubbon, Antonietta Gledhill
RIKILT Wageningen UR and Waters
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Application Notes
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Application Notes
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In this application note, we present a rapid, robust method for the analysis of both regulated and non-regulated lipophilic marine biotoxins in shellfish. Compared to the conventional HPLC/MS/MS method, the speed of analysis increased 4-fold: (from 20 min to 5 min per analysis). This method is also able to meet the regulated levels of detection that can be used instead of the mouse bioassay.

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