Optimized Chromatography for Mass-Directed Purification of Peptides

Library Number:
720000920EN
Part Number:
720000920EN
Author(s):
JoAnn M. Jablonski, Thomas E. Wheat
Source:
Waters
Content Type:
Application Notes
Content Subtype:
Application Notes
Related Products:
 
 

In this study, we illustrate the development of general instrumental parameters and chemical conditions for mass-directed purification of peptides in the range of 8 to 25 residues. A refined protocol for translating a rapid pilot separation to an optimal preparative separation is demonstrated. Peptide compound isolation is more efficiently and effectively obtained using optimized chromatography and mass-directed purification.

 


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