MetaboQuan-R for Acylcarnitines in Human Serum: A Rapid, Targeted UPLC-MS/MS Method for Metabolomic Research Studies

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Billy Joe Molloy
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This technology brief demonstrates a high-throughput UPLC-MS/MS research method for the quantitative analysis of acylcarnitines in human serum samples, without the need for derivitization.

A rapid UPLC-MS/MS methodology has been developed for the research analysis of acylcarnitines. This method has been demonstrated to be suitable for the analysis of physiologically relevant levels of these analytes in human serum. This method utilizes a generic LC-MS platform that can be used for various compound classes (including metabolomics, lipidomics, and proteomics), meaning it can be applied as part of a suite of analyses that are run subsequently as part of a targeted multi-omics workflow.

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