This technology brief demonstrates the use of Empower 3 MS Peak Tracking in the tracking of peak elution during development of a UPLC method for metoclopramide HCl and related substances by mass detection.
Utilizing the Empower 3 MS Peak Tracking enables users to correctly track retention time of each component in a sample mixture by mass detection. Empower can quickly display results generated from multiple experimental runs in a report to show retention time of each peak summarized by the mass-to-charge ratio. This streamlines the entire method development processes by accurately tracking selectivity changes of each component over different experiments. Combining UV with MS increases the efficiency of developing robust and reliable methods, and improving overall laboratory throughput.