Single Quadrupole Mass Detection
Tandem Quadrupole ( Triple Quadrupole ) Mass Spectrometry
Time-of-flight Mass Spectrometry
Quadrupole Time-of-flight Mass Spectrometry
Ion Mobility Mass Spectrometry
In this application note, we demonstrate peptide mapping and monitoring capabilities of the BioAccord System using forced degradation study of a monoclonal antibody (mAb) as a case study.
The BioAccord System controlled by compliant-ready UNIFI Software is purposefully designed with integrated methods for routine therapeutic protein analysis. It can perform routine peptide characterization and accurate mass screening for CQA monitoring. The seamless integration of the two peptide analyses through the custom library feature is an effective way of transferring knowledge from characterization to monitoring that can be deployed across different analytical laboratory settings.
Further, the SmartMS System with intuitive informatics control (with promoted tune parameters, automated instrument health status monitoring, and calibration) provides a robust MS system suitable for users with any skill level.
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