Complementing Routine Peptide Monitoring Using the ACQUITY QDa Mass Detector

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Robert Birdsall, Eoin Cosgrave, and Sean M. McCarthy
Waters Corp.
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Application Notes
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Application Notes
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The ACQUITY QDa Detector is Waters’ solution to meet the demands of today’s fast-paced biopharmaceutical quality control laboratories by enabling complementary optical and mass spec analysis techniques to be run on-line in a single screening workflow for improved productivity in data analysis.

In this application note, we demonstrate the use of the ACQUITY QDa Detector as an orthogonal detection technique that enables the integration of optical (UV) and basic mass spectral data within a single UPLC workflow using a known peptide mixture.

By enabling efficient data acquisition and analysis within compliant-ready Empower 3 CDS Software, the ACQUITY QDa Detector is a powerful tool that can increase productivity and confidence in data analysis within the biopharmaceutical production environment.

Read our follow-up application note, Adding Mass Detection to Routine Peptide-Level Biotherapeutic Analyses with the ACQUITY QDa Detector

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