A New Separation Tool for a Broad Range of Analytical Challenges: UltraPerformance Convergence Chromatography - Chromatography Today, Nov/Dec 2012

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Christopher J. Hudalla, Patrick D. McDonald
Chromatography Today
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Scientific Publications
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In 2012, new technology was introduced that may finally enable the realization of J. Calvin Giddings’ vision of convergence chromatography. UltraPerformance Convergence Chromatography (UPC2) precisely pumps supercritical CO2 as the predominant mobile phase solvent through small-particle stationary phases offering a wide range of selectivity. UPC2 delivers high efficiency, shorter separation times, reduced solvent consumption, streamlined sample preparation, and lower cost of analysis per sample (often a savings of > 95%).


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