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  • Investigation of protein induction in tumour vascular targeted strategies by MALDI MSI

    Content Type: Journal Citations | Content Subtype: - Format: | Date(s): July 04, 2012
    Characterising the protein signatures in tumours following vascular-targeted therapy will help determine both treatment response and resistance mechanisms.
  • Size, weight and position: ion mobility spectrometry and imaging MS combined

    Content Type: Journal Citations | Content Subtype: - Format: | Date(s): July 04, 2012
    This paper reviews the evolution of ion-mobility-based imaging mass spectrometry and provides examples of its application in analytical studies of biological surfaces.
  • Matrix-assisted laser desorption ionization imaging mass spectrometry in lipidomics

    Content Type: Journal Citations | Content Subtype: - Format: | Date(s): July 04, 2012
    The relevant structural, energetics, and regulatory roles of lipids are universally acknowledged.
  • Ion mobility mass spectrometry for peptide analysis

    Content Type: Journal Citations | Content Subtype: - Format: | Date(s): July 02, 2012
    This paper describes the application of IM-MS to the study of peptides.
  • Massenspektrometrie mit einer neuen Dimension

    Content Type: Journal Citations | Content Subtype: - Format: | Date(s): July 02, 2012
    Bei der Analyse komplexer Proteinmischungen spielt die Massenspektrometrie heute eine zentrale Rolle.
  • A concise review of mass spectrometry imaging

    Content Type: Journal Citations | Content Subtype: - Format: | Date(s): July 03, 2012
    Mass spectrometric imaging allows the investigation of the spatial distribution of molecules at complex surfaces.
  • Real-time reaction monitoring using ion mobility-mass spectrometry

    Content Type: Journal Citations | Content Subtype: - Format: | Date(s): July 03, 2012
    The potential of ion mobility (IM) spectrometry in combination with mass spectrometry (MS) for real-time reaction monitoring is reported.
  • Design, Synthesis, and Traveling Wave Ion Mobility Mass Spectrometry Characterization of Iron(II)– a...

    Content Type: Journal Citations | Content Subtype: - Format: | Date(s): July 04, 2012
    New metallomacrocycles composed of 2,2′:6′,2″-terpyridine (tpy) ligands and RuII or FeII transition metal ions were prepared by stepwise directed assembly and characterized by 2D diffusion NMR spectroscopy (DOSY), electrospray ionization traveling wave io...
  • MALDI-MS imaging of lipids in ex vivo human skin

    Content Type: Journal Citations | Content Subtype: - Format: | Date(s): July 04, 2012
    In this study, we describe the use of MALDI-MS, MS/MS and MS imaging methods for analysing lipids within cross-sections of ex vivo human skin.
  • MALDI Imaging with Ion-Mobility MS: Waters Corporation

    Content Type: Journal Citations | Content Subtype: - Format: | Date(s): July 04, 2012
    For reasons of the unique detection principle based on mass spectrometry, MALDI-IMS provides an attractive proposition for molecular imaging, as a large range of different compounds can be detected simultaneously with simple protocol and fast data acquisi...
  • Lipid analysis and lipidomics by structurally selective ion mobility-mass spectrometry

    Content Type: Journal Citations | Content Subtype: - Format: | Date(s): July 04, 2012
    Recent advances in mass spectrometry approaches to the analysis of lipids include the ability to incorporate both lipid class identification with lipid structural information for increased characterization capabilities.
  • Nanoscale Phase Segregation of Mixed Thiolates on Gold Nanoparticles

    Content Type: Journal Citations | Content Subtype: - Format: | Date(s): July 04, 2012
    Direkter Beweis: Die Phasenseperation und Domänenbildung innerhalb einer Schutzschicht aus Goldnanopartikeln kann (AuNPs) mittels Ionenbeweglichkeitsmassenspektrometrie (IM-MS), einer zweidimensionalen Trennverfahren in der Gasphase, beobachtet werden.
  • Separation and Characterization of Metallosupramolecular Libraries by Ion Mobility Mass Spectrometry

    Content Type: Journal Citations | Content Subtype: - Format: | Date(s): July 04, 2012
    The self-assembly of ZnII ions and bis(terpyridine) (tpy) ligands carrying 120° or 180° angles between their metal binding sites was utilized to prepare metallosupramolecular libraries with the connectivity.
  • Utility of spatially-resolved atmospheric pressure surface sampling and ionization techniques as alt...

    Content Type: Journal Citations | Content Subtype: - Format: | Date(s): July 04, 2012
    Tissue distribution studies of drug molecules play an essential role in the pharmaceutical industry and are commonly undertaken using quantitative whole body autoradiography (QWBA) methods.
  • Electrospray Ionization Tandem Mass Spectrometry of Ammonium Cationized Polyethers

    Content Type: Journal Citations | Content Subtype: - Format: | Date(s): July 02, 2012
    This study shows the potential of specific amines as tools for the structural elucidation of high molar mass polyethers.
  • Characterisation of serpin polymers in vitro and in vivo

    Content Type: Journal Citations | Content Subtype: - Format: | Date(s): July 02, 2012
    Neuroserpin is a member of the serine protease inhibitor or serpin superfamily of proteins.
  • Structural resolution of carbohydrate positional and structural isomers based on gas-phase ion mobil...

    Content Type: Journal Citations | Content Subtype: - Format: | Date(s): July 02, 2012
    This report describes the rapid characterization of positional and structural carbohydrate isomers based on structural separations provided by ion mobility-mass spectrometry (IM-MS).
  • 2. Ion Activation and Mass Analysis in Protein Mass Spectrometry

    Content Type: Journal Citations | Content Subtype: - Format: | Date(s): July 02, 2012
    This chapter contains sections titled: Introduction, Ion Activation and Tandem MS Analysis, Mass Analyzers and References
  • Determination of free desmosine and isodesmosine as urinary biomarkers of lung disorder using ultra ...

    Content Type: Journal Citations | Content Subtype: - Format: | Date(s): July 03, 2012
    The elastin degradation products, desmosine (DES) and isodesmosine (IDES) are highly stable, cross-linking amino-acids that are unique to mature elastin.
  • A concise review of mass spectrometry imaging

    Content Type: Journal Citations | Content Subtype: - Format: | Date(s): July 03, 2012
    This review will describe and discuss a selected number of crucial developments in ionization, instrumentation, and application of this innovative technology. The focus of this review is on the latest developments in imaging MS.
  • Determination of testosterone and epitestosterone glucuronides in urine by ultra performance liquid ...

    Content Type: Journal Citations | Content Subtype: - Format: | Date(s): July 03, 2012
    UPLC-ion mobility spectrometry separations combined with mass spectrometry (UPLC-IM-MS) and tandem mass spectrometry (UPLC-IM-MS/MS) have been investigated for the simultaneous determination of testosterone and epitestosterone glucuronides in urine.
  • Intrinsic Mobility of Gaseous Cationic and Anionic Aggregates of Ionic Liquids

    Content Type: Journal Citations | Content Subtype: - Format: | Date(s): July 03, 2012
    Travelling-wave ion mobility mass spectrometry was used to measure the intrinsic mobility of a series of gaseous supra-cation and supra-anion aggregates of several ionic liquids.
  • Ion mobility mass spectrometry enables the efficient detection and identification of halogenated nat...

    Content Type: Journal Citations | Content Subtype: - Format: | Date(s): July 03, 2012
    Direct observation of halogenated natural products produced by different strains of marine cyanobacteria was accomplished by electrospray ionization and matrix assisted laser desorption ionization and gas phase separation via ion mobility mass spectrometr...
  • Structural Characterization of Unsaturated Phospholipids Using Traveling Wave Ion Mobility Spectrome...

    Content Type: Journal Citations | Content Subtype: - Format: | Date(s): July 03, 2012
    A number of phosphatidylcholine (PC) cations spanning a mass range of 400 to 1000 Da are investigated using electrospray ionization mass spectrometry coupled with traveling wave ion mobility spectrometry (TWIMS).
  • Electron Transfer Dissociation Reveals Changes in the Cleavage Frequencies of Backbone Bonds Distant...

    Content Type: Journal Citations | Content Subtype: - Format: | Date(s): July 02, 2012
    Interrogation of electron transfer dissociation (ETD) mass spectra of peptide amide-to-ester backbone bond substituted analogues (depsipeptides) reveals substantial differences in the entire backbone cleavage frequencies.