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  • IonHance MS-Grade Mobile Phase Additives

    Home > Products > Chromatography Consumables & Columns > Analytical Standards and Reagents > Pharmaceutical and Life Science Standards & Kits > Protein Standards & Kits > IonHance MS-Grade Mobile Phase Additives
    IonHance modifiers can be used for LC and LC-MS techniques, such as reversed-phase separations of proteins, peptides, and small molecules.
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    Ionhance Difluoroacetic Acid Infographic

    Content Type: Marketing/Online Tools | Content Subtype: Infographic Format: PDF File Size: 1212.58kB | Date(s): May 20, 2019
    IonHance DFA - The first available MS-Grade DFA
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    IonHance CX-MS pH Concentrates A and B Infographic

    Content Type: Marketing/Online Tools | Content Subtype: Infographic Format: PDF File Size: 1171.39kB | Date(s): October 28, 2019
    This infographic details the benefits of the IonHance CX-MS pH Concentrates A and B.
  • IonHance CX-MS pH Concentrates A and B Care & Use Manual

    Content Type: User Manuals Date(s): October 28, 2019
    This manual describes how to properly use IonHance CX-MS pH Concentrates A and B.
  • IonHance Difluoroacetic Acid Care and Use Manual

    Content Type: User Manuals Date(s): May 16, 2019
    This manual details about IonHance Difluoroacetic Acid reagent.
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    IonHance Difluoroacetic Acid Super Kit (6 vials)
    Part Number: 176004415
    Waters IonHance Difluoroacetic Acid is an MS-grade mobile-phase additive that can be used for LC and LC-MS techniques, such as reversed-phase separations of proteins, peptides, and small molecules. This reagent has been purified to achieve the low metal (sodium and potassium) content that is necessary for MS compatibility. Each vial of the standard is provided in an approximately 1 mL quantity and is contained within a high quality, chemically resistant PFA vial.

    IonHance Difluoroacetic Acid Super Kit (6 vials)

    Part Number: 176004415
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    IonHance Difluoroacetic Acid (Mobile Phase Kit)
    Part Number: 176010000
    Waters IonHance Difluoroacetic Acid is an MS-grade mobile-phase additive that can be used for LC and LC-MS techniques, such as reversed-phase separations of proteins, peptides, and small molecules. This reagent has been purified to achieve the low metal (sodium and potassium) content that is necessary for MS compatibility. Each vial of the standard is provided in an approximately 1 mL quantity and is contained within a high quality, chemically resistant PFA vial.Both the PFA and LDPE (low density polyethylene) containers are rigorously QC tested to ensure less than 100 ppb levels of sodium and potassium to achieve exquisitely high quality mass spectra. This product includes two 1.1 mL IonHance DFA vials and two 1000 mL LDPE mobile phase bottles to maintain the high levels of purity IonHance has to offer. *Disclaimer: Reference values for RM 8671 are not certified to be in correspondence with any Report of Investigation offered by the National Institute of Standards and Technology (NIST). If it is desirable to have such correspondence, it is advised that RM 8671 be directly acquired from NIST (nist.gov).

    IonHance Difluoroacetic Acid (Mobile Phase Kit)

    Part Number: 176010000
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    IonHance Difluoroacetic Acid (1 vial)
    Part Number: 186009201
    Waters IonHance Difluoroacetic Acid is an MS-grade mobile-phase additive that can be used for LC and LC-MS techniques, such as reversed-phase separations of proteins, peptides, and small molecules. This reagent has been purified to achieve the low metal (sodium and potassium) content that is necessary for MS compatibility. Each vial of the standard is provided in an approximately 1 mL quantity and is contained within a high quality, chemically resistant PFA vial..

    IonHance Difluoroacetic Acid (1 vial)

    Part Number: 186009201
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    Promotional IonHance Wrenches, 2/pk
    Part Number: 600001771
    This wrench set is comprised of two wrenches, each with 18mm and 22mm openings designed to facilitate the opening of tubes and vials that are torqued to greater than 3 inch pounds.

    Promotional IonHance Wrenches, 2/pk

    Part Number: 600001771
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    Online IEX-MS of mAb Charge Variants Using a BioResolve SCX mAb Column, IonHance CX-MS pH Concentrat...

    Content Type: Application Notes | Content Subtype: Application Notes Format: PDF File Size: 811.03kB | Date(s): October 28, 2019
    A direct IEX-MS method with broad utility for the successful detection of mAb charge variants.
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    IonHance CX-MS pH Concentrate A, pH 5 in MS Certified LDPE Container (10X Concentrate)
    Part Number: 186009280
    Designed alongside the BioResolve SCX columns, the IonHance CX-MS pH 10X Concentrate A, in MS Certified LDPE Container, was carefully optimized for use in creating a gradient for LC/MS analysis of mAb charge variant separations.

    IonHance CX-MS pH Concentrate A, pH 5 in MS Certified LDPE Container (10X Concentrate)

    Part Number: 186009280
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    IonHance CX-MS pH Concentrate B pH 8.5 in MS Certified LDPE Container (10X Concentrate)
    Part Number: 186009281
    Designed alongside the BioResolve SCX columns, the IonHance CX-MS pH 10X Concentrate B,  in MS Certified LDPE Container, was carefully optimized for use in creating a  gradient for LC/MS analysis of mAb charge variant separations. 

    IonHance CX-MS pH Concentrate B pH 8.5 in MS Certified LDPE Container (10X Concentrate)

    Part Number: 186009281
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    IonHance CX-MS pH Concentrates A & B Kit in MS Certified LDPE Containers  (10X Concentrates)
    Part Number: 176004498
    Designed alongside the BioResolve SCX columns, the IonHance CX-MS pH 10X Concentrates A and B, in MS Certified LDPE Containers, were carefully optimized for use in creating a pH 5.0 to 8.5 gradient for LC/MS analysis of mAb charge variant separations.

    IonHance CX-MS pH Concentrates A & B Kit in MS Certified LDPE Containers  (10X Concentrates)

    Part Number: 176004498
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    BioResolve SCX mAb 3 µm Column (2.1 x 100mm) plus Humanized mAb Mass Check Standard plus IonHance C...
    Part Number: 176004502
    BioResolve SCX mAb, 3 μm, corrosion–resistant column (2.1 x 100) contains non-porous, polymer-based particles grafted with a rigorously-optimized, multi-component network of negatively charged sulfonic acid ligands. This innovative column technology, delivers reproducible, high-resolution, charged-based separations of mAbs and other proteins in both LC and LC-MS applications using robust salt or pH gradient methods. This IEX-MS startup kit also includes one vial of Humanized mAb Mass Check Standard (P/N 186009125), one bottle of IonHance CX-MS pH Concentrate A (pH 5.0) and one bottle of IonHance CX-MS pH Concentrate B (pH 8.5) both in MS Certified LDPE Containers.

    BioResolve SCX mAb 3 µm Column (2.1 x 100mm) plus Humanized mAb Mass Check Standard plus IonHance C...

    Part Number: 176004502
  • info
    BioResolve SCX mAb 3 µm Column (2.1 x 50mm)  plus Humanized mAb Mass Check Standard plus IonHance CX...
    Part Number: 176004500
    BioResolve SCX mAb, 3 μm, corrosion–resistant column (2.1 x 50) contains non-porous, polymer-based particles grafted with a rigorously-optimized, multi-component network of negatively charged sulfonic acid ligands. This innovative column technology, delivers reproducible, high-resolution, charged-based separations of mAbs and other proteins in both LC and LC-MS applications using robust salt or pH gradient methods. This IEX-MS startup kit also includes one vial of Humanized mAb Mass Check Standard (P/N 186009125), one bottle of IonHance CX-MS pH Concentrate A (pH 5.0) and one bottle of tonHance CX-MS pH Concentrate B (pH 8.5) both in MS Certified LDPE Containers.

    BioResolve SCX mAb 3 µm Column (2.1 x 50mm)  plus Humanized mAb Mass Check Standard plus IonHance CX...

    Part Number: 176004500
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    Low Adduct Peptide LC-MS Obtained with IonHance DFA and Certified LDPE Containers

    Content Type: Application Notes | Content Subtype: Technical Notes Format: PDF File Size: 432.46kB | Date(s): June 14, 2019
    Minimizing metal ion contamination for low adduct LC-MS separations using high purity mobile phase additives and containers.
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    BioResolve SCX mAb 3 µm Column (2.1 x 100mm) with VanGuard FIT plus Humanized mAb Mass Check Standar...
    Part Number: 176004501
    BioResolve SCX mAb, 3 μm, corrosion–resistant column (2.1 x 100 with VanGuard Fit) contains non-porous, polymer-based particles grafted with a rigorously-optimized, multi-component network of negatively charged sulfonic acid ligands. This innovative column technology, delivers reproducible, high-resolution, charged-based separations of mAbs and other proteins in both LC and LC-MS applications using robust salt or pH gradient methods. This IEX-MS startup kit also includes one vial of Humanized mAb Mass Check Standard (P/N 186009125), one bottle of IonHance CX-MS pH Concentrate A (pH 5.0) and one bottle of IonHance CX-MS pH Concentrate B (pH 8.5) both in MS Certified LDPE Containers.

    BioResolve SCX mAb 3 µm Column (2.1 x 100mm) with VanGuard FIT plus Humanized mAb Mass Check Standar...

    Part Number: 176004501
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    IEX-MS Start Up Kit: BioResolve SCX mAb 3 µm Column (2.1 x 50mm) with VanGuard FIT plus Humanized mA...
    Part Number: 176004499
    BioResolve SCX mAb, 3 μm, corrosion–resistant column (2.1 x 50 with VanGuard Fit) contains non-porous, polymer-based particles grafted with a rigorously-optimized, multi-component network of negatively charged sulfonic acid ligands. This innovative column technology, delivers reproducible, high-resolution, charged-based separations of mAbs and other proteins in both LC and LC-MS applications using robust salt or pH gradient methods. This IEX-MS startup kit also includes one vial of Humanized mAb Mass Check Standard (P/N 186009125), one bottle of IonHance CX-MS pH Concentrate A (pH 5.0) and one bottle of tonHance CX-MS pH Concentrate B (pH 8.5) both in MS Certified LDPE Containers.

    IEX-MS Start Up Kit: BioResolve SCX mAb 3 µm Column (2.1 x 50mm) with VanGuard FIT plus Humanized mA...

    Part Number: 176004499
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    Comparing Mobile Phase Additives for the Separation of mAb Tryptic Peptides: A Case Study on Formic,...

    Content Type: Application Notes | Content Subtype: Application Notes Format: PDF File Size: 2632.94kB | Date(s): October 03, 2019
    The chromatographic and MS performance of DFA peptide mapping is compared against traditional approaches based on FA and TFA.
  • Improved characterization of IgG2 isoforms by LC-MS webinar

    Web Page | Date: September 20, 2019 In this webinar, Stuart Wright from Sartorius Stedim BioOutsource will share his journey into developing an LC-MS method combining both high resolution and a excellent sensitivity.