VanGuard Column Protection

Extend Analytical Column Lifetime

VanGuard Pre-columns and Cartridges are optimized to protect and prolong analytical column lifetimes without compromising chromatographic performance. These column protection products are available in a wide selection of particle sizes and stationary phases making them ideally suited for the physical and chemical protection for all Waters analytical columns.

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Removes Particulates and Chemical Contamination

The often complex sample matrices encountered in pharmaceutical, natural product, environmental, and industrial chemical analysis prematurely shorten analytical column lifetime and degrade chromatographic performance. Waters VanGuard Column Protection products help improve analytical column performance by removing particulate and chemical contamination that may be present in the mobile-phase stream.

Column Protection Benefits

Feature	Benefit
First guard column for UPLC and UHPLC applications	Guaranteed compatibility with pressures up to 18,000 PSI
Patent pending, ultra-low volume design	Minimal chromatographic effects
Manufactured using Waters column hardware, particles, and sorbent chemistries	Superior HPLC, UHPLC, and UPLC column protection and performance
Connects directly to Waters HPLC, XP, UHPLC, and UPLC columns	Leaks and connection voids are eliminated

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Pre-columns Maintain UPLC Column Efficiency

The one-piece, patented design of the VanGuard Pre-columns does not compromise the holistic approach to higher efficiency, greater resolution, and increased throughput of ACQUITY UPLC separations. The low dispersion 2.1 x 5 mm these pre-column connects directly to the inlet of the ACQUITY UPLC Column and is available in all ACQUITY UPLC Column stationary phases.

Cost Effective Protection for HPLC and UHPLC Columns

These Cartridge Columns are a universal solution to extend all HPLC and UHPLC column lifetime. Simply replace the cartridge instead of your more expensive analytical column to regenerate the original separation performance. The reusable holder is designed with an adjustable ferrule so that it can be attached to any column inlet.

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Reference Guide for VanGuard Pre-columns and Cartridge Columns

Maintain HPLC/UHPLC Separation Efficiency

These Column Protection products have been optimized to provide minimal chromatographic effects under a wide variety of separation conditions. The low dead volume design minimizes chromatographic peak dispersion and tailing to maintain separation resolution and efficiency.

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Installation

This short video demonstrates the proper installation of these Cartridge Columns.

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