Mass Spectrometry Software to Facilitate LC-MS Analysis in Clinical Laboratories

Waters MassLynx Software complements your LC-MS/MS system with its intuitive user interface, intelligent instrument control, and software features built around the focus of your diagnostic analysis: the patients sample. With much of its capabilities driven by input from our extensive user base, MassLynx has evolved into a powerful software package that delivers the versatility and flexibility your laboratory requires.

The TargetLynx Application Manager automates sample data processing and reporting of quantitative results from LC-MS/MS acquisitions using multiple reaction monitoring (MRM), selected ion monitoring (SIM) or full scan/spectrum approaches. Beyond the expected capabilities of any quantitative data package, TargetLynx Application Manager can incorporate a range of confirmatory checks on a data set.

TargetLynx Application Manager can be used to identify and flag samples that exceed user-defined thresholds where:

• Analytes exceed a concentration threshold
• Analyte confirmatory ion ratios are outside specified limits
• One or more analyte signal-to-noise ratios are below a defined value
• An analyte retention time or relative retention time is outside limits
• An analyte concentration is below set LOD and LOQ thresholds
• The standard deviation of response for QC standards exceeds a defined value
• The blank response is too high
• The coefficient of determination (r2) of the calibration curve exceeds a defined value

For in vitro diagnostic use. Not available in all countries. For information on availability, please contact your local representative.