DESI - MS Imaging for Biomedical Research

Understand molecular visualization and spatial distribution of compounds.

The spatial distribution of molecular species in a sample can provide a wealth of information about biological, chemical and physiological processes. Mass spectrometry imaging (MSI) with Desorption Electrospray Ionization Mass Spectrometry (DESI) produces label-free, multiplexed and objective measurement of molecular targets from complex surfaces. This direct-from-sample analytical technique provides researchers with the information needed to quickly and objectively interpret molecular profiles and make confident decisions based on definitive data.

DESI is a soft ionization technique performed under ambient environmental conditions and requires little to no sample preparation. It is minimally invasive, making it suitable for direct tissue analysis and has potential to provide non-subjective information about biochemical distribution of molecules after just one measurement.

  • Ambient analysis technique to visualize the spatial localization and distribution of molecules
  • No sample preparation. Collect molecular information directly from tissue samples
  • Compatible with current histopathological workflows such as H&E Staining
  • Measure small molecule drugs, lipid and endogenous metabolites.
  • Overview