Engineered with bio-inert flow paths made of iron-free materials, the ACQUITY Arc Bio System keeps large molecules intact and on the move, for better sample recovery and minimal carryover, whether the chromatographic mode is reversed phase (RP), ion exchange (IEX), size exclusion (SEC), or hydrophobic interaction (HIC).
Built upon the reliable foundation of the ACQUITY Arc System, the ACQUITY Arc Bio System is designed with novel Arc Multi-flow path technology to provide the versatility and robustness required to efficiently transfer, adjust, or improve your methods without compromising method integrity.
Reliable operation under demanding conditionsAssays utilizing SEC, IEX and HIC modes of chromatography typically utilize high ionic strength mobile phases, often under basic or acidic conditions. The ACQUITY Arc Bio System’s flow paths are made of bio-inert materials to minimize undesirable protein interactions and maximize system robustness under salt and pH extremes. The result: a system that is ideally suited for routine, trouble-free operation with negligible carryover and maximum recovery of biomolecules for consistently high system performance. |
Replicate your existing methodsAnalytical laboratories can’t afford to use anything but the most reliable and robust equipment to ensure product consistency and compliance with regulatory guidelines. Analytical laboratories must also commonly transfer methods across the organization, or to contract partners, while preserving method integrity. Upgrade your analytical laboratory with the ACQUITY Arc Bio System, a versatile, biocompatible LC system that delivers HPLC and UHPLC method compatibility at the flip of a switch. |
Streamline your method developmentThe bioQuaternary Solvent Manager automatically blends mobile phase combinations and gradients on demand, enabling you to achieve retention and critical resolution requirements for your analysis. Designed with bio-inert materials, the bioQuaternary Solvent Manager accommodates the range of aqueous, high ionic strength mobile phases and organic solvents used in several biopharmaceutical LC applications. Auto•Blend Plus Technology extends traditional quaternary solvent blending to permit gradient programming directly in units of pH and ionic strength, providing the ability to vary composition in even the smallest increments of pH (even those differing by 0.1 pH units or less). |
Develop methods that stand the test of timeThe ACQUITY Arc Bio System is fully compatible with the ACQUITY QDa Mass Detector, supporting efficient and robust method development by expanding the information you can get from your system using the same Empower Software. The system automatically pairs qualitative mass spectral data to the peaks in your chromatogram leaving nothing to chance.
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