Xevo G2-XS Tof Time-of-Flight Mass Spectrometry

Maximum robustness with no compromise in performance

The trend for increasing complexity of both samples and studies can result in difficulty obtaining high quality data for every component of interest while maintaining optimum performance throughout the analysis.

 The Xevo® G2-XS Tof combines StepWave^TM ion optics with the XS Collision Cell, providing a significant increase in sensitivity with no reduction in selectivity.  During long analyses, critical hardware components stay clean for longer, so results are more reproducible and the laboratory stays productive.

 Meaningful information is obtained for a greater number of components across a larger population of samples than ever before, giving a more complete picture for improved understanding and more confident decision making.

Highest quality, most comprehensive qualitative and quantitative information

Complete understanding of a sample requires detailed and accurate qualitative and quantitative information for every component of interest, collected on a fast timescale in order to access the full benefits of modern separation techniques.

 MS^E is a simple but powerful approach that delivers accurate mass precursor and fragment ion data for every detectable component, whether chromatographically resolved or not.  This represents the ultimate in qualitative information, with the same data also providing accurate quantitative profiles.  And because the approach is un-targeted, the data can be interrogated again at a later date as scientific questions evolve.

Flexibility to adapt to changing needs

The growing emphasis on efficiency and productivity in the laboratory demands analytical systems that are not only robust and reliable, but that also have the flexibility to accomplish a wide variety of tasks today, with future-proofing for the innovations of tomorrow. 

Waters’ Universal Ion Source Architecture enables the use of a single analytical platform for many different applications and molecule types, as well as providing the option to add new functionality as requirements and priorities change.  All source options are designed to be quickly interchangeable and ready to use within minutes, maximizing versatility and minimizing downtime.

Accessible to experts and non-experts alike

Traditionally the ability to achieve and maintain optimum performance from such a powerful analytical system would require a level of knowledge and experience held only by expert users.

The Xevo G2-XS Tof features IntelliStart^TM technology, an intuitive user interface that automates routine tasks and ensures reproducible data of the highest quality, ensuring the full capability of the system is accessible to all.

IntelliStart enables essential functions to be carried out automatically:

• MS resolution and calibration checks
• Simple setup of diverse experiments
• Scheduled LC-MS system checks
• Continuous system monitoring

Upgrade path to full QTof functionality

To address increasing demands and challenges, the Xevo G2-XS Tof can be upgraded in-situ to full QTof functionality with minimal disruption to the busy laboratory.  This upgrade enables powerful features that further enhance the capability and versatility of the analytical system: 

• Tof-MRM for class-leading quantitative performance in real everyday laboratory conditions, demonstrated by limits of detection and quantification superior to anything achieved before with high resolution MS. 
• FastDDA for automated, targeted data acquisition providing rapid, intelligent accurate mass MS/MS capability for confirmation of known compounds or characterization of unknowns, in situations where only true MS/MS data will suffice.