Prep 100q SFC System

When "eco-friendly” is an important consideration for today’s purification labs.

Note: This product has been replaced by the SFC 150 AP System.

The Prep 100q SFC System is critically important to those prep labs aspiring to be more “green,” as it uses environmentally-friendly carbon dioxide (CO₂) as the primary mobile phase.

Designed for semi-prep to preparative applications (100mL/min) for purification of milligrams to multiple grams of product.
Maximum purity and compound recovery with our Gas-Liquid Separator technology (patent pending).
Fully automated open-bed sample injection and fraction collection allows for the processing of hundreds of samples or just a few.

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A Greener Alternative to High-Throughput Purification

The Waters Prep 100q SFC System provides high-throughput, semi-preparative to preparative scale purification, meeting the increased demand for higher productivity, greater flexibility, and lower costs per sample.

The only open-bed preparative scale SFC system on the market today, the Prep 100q SFC System is the ideal platform for a wide variety of purification applications: chiral and achiral separations, impurity isolation, natural products, and purification of standards and libraries of drug-like compounds. Waters’ patent-pending Gas Liquid Separator (GLS) technology manages the decompression of CO₂and its removal from the liquid stream in a highly effective manner, allowing for more efficient fraction collection in an open-bed environment. This proprietary, innovative technology results in high recovery of your valuable compounds and gives you the confidence that nothing was left behind.

Leveraging the benefits of green purification technology, the Prep 100q SFC System utilizes CO₂ as the primary mobile phase, which is a beneficial alternative for laboratories overwhelmed with solvent disposal and time-consuming sample dry-down.

Compound Purification with Confidence

The Prep 100q SFC system is designed with flexibility in mind. Versatile configurations allow for the simplicity of UV-directed collection, or the specificity of MS-directed collection, as laboratory requirements change, meeting the needs of the most demanding applications.

zoom	Traditional UV-Directed Purification Powerful, versatile, and robust, UV-based purification is simple to implement and easy to use, and is ideally used for samples containing multiple unknown compounds.

MS-Directed Purification for Ultimate Specificity

When fraction collection is triggered by mass detection, only the mass of interest is collected, thus fewer fractions need to be dried down and re-analyzed, increasing throughput and lowering per sample costs. This highly efficient and specific technique generates both MS and UV spectral data on all peaks, but only targets known compounds. This configuration is capable of collections with UV-directed, MS-directed, or mixed mode techniques.

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Unattended Operation for Enhanced Productivity

Waters' easy-to-use systems and software allow samples to be run with unattended system operation. This improves productivity by enabling chemists to focus on their results rather than on the instrument.

Waters' FractionLynx Application Manager provides full-cycle automation, from collection of the detected fractions, to tracking the samples and fractions, to presentation of the data in an easy-to-view format.
Unique method-filtering software enables the user to quickly choose a method from the existing library of methods.
Remote system status monitor tracks the sample queue status, instrument status, and current running sample status while providing information on system usage.
With Open Access Software, chemists can simply enter their sample into a system and have results delivered to their desktop, while an administrator monitors the system and manages instrument access.

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