Waters offers a comprehensive range of analytical system solutions, software, and services for scientists. Liquid Chromatography. Mass Spectrometry. Waters is the leading provider of lab equipment, supplies and software for scientists across the world. Easily research and order everything your lab needs! Waters offers a comprehensive range of analytical system solutions, software, and services for scientists. Liquid Chromatography. Mass Spectrometry. Waters is the leading provider of lab equipment, supplies and software for scientists across the world. Easily research and order everything your lab needs!
SKU: 186008947 BioResolve RP mAb Polyphenyl VanGuard Cartridge, 450Å, 2.7 µm, 3.9 mm X 5 mm, 3/pk
BioResolve RP mAb Polyphenyl VanGuard Cartridge, 450Å, 2.7 µm, 3.9 mm X 5 mm Columns contain 2.7 µm superficially-porous-silica particles having an average pore diameter of 450Å. The particles are functionalized with a proprietary polyphenyl bonding process that was specifically designed for LC or LC-MS analyses of intact IgG monoclonal antibodies and their fragments. This Part Number contains (3) VanGuard Cartridges.
Note: The VanGuard Universal Cartridge Holder (p/n: 186007949) is required for use with these replaceable cartridges. p/n: 176004161 contains (3), 3.9 x 5mm VanGuard Cartridges as well as an included VanGuard Universal Cartridge Holder (p/n: 186007949).
This guard column is compatible with:
p/n: 186008953 BioResolve RP mAb Polyphenyl Column, 450Å, 2.7 µm, 4.6 mm X 50 mm
p/n: 186008954 BioResolve RP mAb Polyphenyl Column, 450Å, 2.7 µm, 4.6 mm X 100 mm
p/n: 186008955 BioResolve RP mAb Polyphenyl Column, 450Å, 2.7 µm, 4.6 mm X 150 mm
p/n: 176004167 BioResolve RP mAb Polyphenyl Column, 450Å, 2.7 µm, 4.6 mm X 50 mm w/ Standards
p/n: 176004168 BioResolve RP mAb Polyphenyl Column, 450Å, 2.7 µm, 4.6 mm X 100 mm w/ Standards
p/n: 176004169 BioResolve RP mAb Polyphenyl Column, 450Å, 2.7 µm, 4.6 mm X 150 mm w/ Standards
Engineered for scientists working at the forefront of biopharmaceutical analysis, the BioResolve RP mAb Polyphenyl VanGuard Cartridge (450Å, 2.7 µm, 3.9 mm x 5 mm) is purpose-built to enhance the robustness and lifetime of BioResolve RP mAb Polyphenyl analytical columns. Each cartridge contains superficially porous silica particles with a large 450Å pore size, ideal for intact monoclonal antibody (mAb) and fragment separations. These particles are bonded with a proprietary polyphenyl ligand, optimized for reversed-phase LC and LC-MS workflows targeting IgG mAbs and their subunits.
This part number includes three VanGuard guard cartridges. To operate them effectively, you'll need the Note: The VanGuard Universal Cartridge Holder (p/n: 186007949) is required for use with these replaceable cartridges. p/n: 176004161 contains (3), 3.9 x 5mm VanGuard Cartridges as well as an included VanGuard Universal Cartridge Holder (p/n: 186007949).
This guard column is compatible with:
p/n: 186008953 BioResolve RP mAb Polyphenyl Column, 450Å, 2.7 µm, 4.6 mm X 50 mm
p/n: 186008954 BioResolve RP mAb Polyphenyl Column, 450Å, 2.7 µm, 4.6 mm X 100 mm
p/n: 186008955 BioResolve RP mAb Polyphenyl Column, 450Å, 2.7 µm, 4.6 mm X 150 mm
p/n: 176004167 BioResolve RP mAb Polyphenyl Column, 450Å, 2.7 µm, 4.6 mm X 50 mm w/ Standards
p/n: 176004168 BioResolve RP mAb Polyphenyl Column, 450Å, 2.7 µm, 4.6 mm X 100 mm w/ Standards
p/n: 176004169 BioResolve RP mAb Polyphenyl Column, 450Å, 2.7 µm, 4.6 mm X 150 mm w/ Standards","productType":"Guards","thumbnailURL":"https://www.waters.com/content/dam/waters/en/brand-assets/thumbnails/icon-columns.jpg.thumb.319.319.png"},{"name":"VanGuard Cartridge Holder, 1/pk","webCategory":"Columns","pageUrl":"https://www.waters.com/nextgen/ph/en/shop/columns/186008947-bioresolverp-mabpolyphenyl-vanguard-cartridge-450a-27--m-39-mm-x.html","sku":"186007949","message":"","productType":"Guards","thumbnailURL":"https://www.waters.com/content/dam/waters/en/Photography/Products/consumables/vials-plates-cartridges/vanguard-cartridge-holder-hero.jpg.thumb.319.319.png"},{"name":"TruView pH Control LCMS Certified Clear Glass, 12 x 32 mm, Screw Neck Vial, with Cap and preslit PTFE/Silicone Septum, 2 mL Volume, 100/pk","webCategory":"VialsContainers&CollectionPlates","pageUrl":"https://www.waters.com/nextgen/ph/en/shop/columns/186008947-bioresolverp-mabpolyphenyl-vanguard-cartridge-450a-27--m-39-mm-x.html","sku":"186005666CV","message":"TruView pH Control LCMS Certified Vials are produced following tightly controlled manufacturing processes and handling procedures. They are tested for cleanliness by mass spectrometers and for low analyte adsorption by LC-MS/MS.","productType":"Vials","thumbnailURL":"https://www.waters.com/content/dam/waters/en/Photography/Products/skus/vials-and-plates/clear-12x32-screw-neck-vial-certified-black-cap.jpg.thumb.319.319.png"},{"name":"Intact mAb Mass Check Standard","webCategory":"StandardsReagents","pageUrl":"https://www.waters.com/nextgen/ph/en/shop/columns/186008947-bioresolverp-mabpolyphenyl-vanguard-cartridge-450a-27--m-39-mm-x.html","sku":"186006552","message":"Analysis of intact proteins by MS is a powerful approach for protein identification and assignment of protein modifications. The Intact mAb Mass Check Standard is a LC/MS standard used as a qualitative tool for intact mass analysis. It is an intact mouse protein purified by Protein-A with a known molecular weight, ideal for higher molecular weight intact mass measurements. It is provided in a Waters Max Recovery Vial PN 18600327c. This standard is designed to be used for routine MS optimization, system setup and performance testing.","productType":"Standards","thumbnailURL":"https://www.waters.com/content/dam/waters/en/Photography/Products/skus/reagents/clear-vial-2mL-black-cap.jpg.thumb.319.319.png"},{"name":"MassPREP Protein Standard Mix","webCategory":"StandardsReagents","pageUrl":"https://www.waters.com/nextgen/ph/en/shop/columns/186008947-bioresolverp-mabpolyphenyl-vanguard-cartridge-450a-27--m-39-mm-x.html","sku":"186004900","message":"The MassPREP Protein Standard Mix consists of Ribonuclease A, Cytochrome c, bovine serum Albumin, Myoglobin, Enolase, and Phosphorylase b. This mixture contains proteins that vary in isoelectric points, molecular weights and hydrophobicities. These characteristics provide the user with an attractive intact protein mixture that can be used for a variety of applications. It is recommended that this standard be used on a regular basis for benchmarking column and system performance, similar to the QCRM product line.","productType":"Standards","thumbnailURL":"https://www.waters.com/content/dam/waters/en/Photography/Products/skus/reagents/clear-vial-2mL-black-cap.jpg.thumb.319.319.png"},{"name":"BioResolve RP mAb Polyphenyl VanGuard Cartridge w/holder, 450Å, 2.7 µm, 3.9 mm X 5 mm, 3/pk","webCategory":"Columns","pageUrl":"https://www.waters.com/nextgen/ph/en/shop/columns/186008947-bioresolverp-mabpolyphenyl-vanguard-cartridge-450a-27--m-39-mm-x.html","sku":"176004161","message":"
BioResolve RP mAb Columns contain 2.7-μm superficially-porous-silica particles having an average pore diameter of 450Å. The particles are functionalized with a proprietary polyphenyl bonding process that was specifically designed for LC or LC-MS analyses of intact IgG monoclonal antibodies and their fragments. This Part Number contains (3) VanGuard Cartridges as well as an included VanGuard Universal Cartridge Holder (P/N 186007949). \n
","productType":"Guards","thumbnailURL":"https://www.waters.com/content/dam/waters/en/brand-assets/thumbnails/icon-columns.jpg.thumb.319.319.png"},{"name":"BioResolve RP mAb Polyphenyl Column, 450Å, 2.7 µm, 4.6 mm X 50 mm, 1/pk w/ Intact mAb and mAb Subunit Standards","webCategory":"Columns","pageUrl":"https://www.waters.com/nextgen/ph/en/shop/columns/186008947-bioresolverp-mabpolyphenyl-vanguard-cartridge-450a-27--m-39-mm-x.html","sku":"176004167","message":"BioResolve RP mAb Columns contain 2.7 µm superficially-porous-silica particles having an average pore diameter of 450 Å. The particles are functionalized with a proprietary polyphenyl bonding process that was specifically designed for LC or LC-MS analyses of intact IgG monoclonal antibodies and their fragments. This p/n: also includes one vial of the Intact mAb Mass Check Standard (p/n: 186006552) and one vial of the mAb Subunit Standard (p/n: 186008927).","productType":"Columns","thumbnailURL":"https://www.waters.com/content/dam/waters/en/brand-assets/thumbnails/icon-columns.jpg.thumb.319.319.png"},{"name":"BioResolve RP mAb Polyphenyl Column, 450Å, 2.7 µm, 4.6 mm X 100 mm, 1/pk with Intact mAb and mAb Subunit Standards","webCategory":"Columns","pageUrl":"https://www.waters.com/nextgen/ph/en/shop/columns/186008947-bioresolverp-mabpolyphenyl-vanguard-cartridge-450a-27--m-39-mm-x.html","sku":"176004168","message":"BioResolve RP mAb Columns contain 2.7 µm superficially-porous-silica particles having an average pore diameter of 450 Å. The particles are functionalized with a proprietary polyphenyl bonding process that was specifically designed for LC or LC-MS analyses of intact IgG monoclonal antibodies and their fragments. This p/n: also includes one vial of the Intact mAb Mass Check Standard (p/n: 186006552) and one vial of the mAb Subunit Standard (p/n: 186008927).","productType":"Columns","thumbnailURL":"https://www.waters.com/content/dam/waters/en/brand-assets/thumbnails/icon-columns.jpg.thumb.319.319.png"},{"name":"BioResolve RP mAb Polyphenyl Column, 450Å, 2.7 µm, 4.6 mm X 150 mm, 1/pk w/ Intact mAb and mAb Subunit Standards","webCategory":"Columns","pageUrl":"https://www.waters.com/nextgen/ph/en/shop/columns/186008947-bioresolverp-mabpolyphenyl-vanguard-cartridge-450a-27--m-39-mm-x.html","sku":"176004169","message":"
BioResolve RP mAb Columns contain 2.7-μm superficially-porous-silica particles having an average pore diameter of 450Å. The particles are functionalized with a proprietary polyphenyl bonding process that was specifically designed for LC or LC-MS analyses of intact IgG monoclonal antibodies and their fragments. This P/N also includes one vial of the Intact mAb Mass Check Standard (P/N 186006552) and one vial of the mAb Subunit Standard (P/N 186008927).
Waters mAb Subunit Standard can be used in the benchmarking of LC and LC-MS techniques, proficiency testing among different instruments and laboratories, and system suitability. This standard is a filtered and stabilized formulation of reduced, IdeS-digested NIST Reference Material 8671 (NIST mAb), a humanized IgG1κ expressed from a murine cell line. Each vial of the standard is provided in an approximately 25 μg quantity.
