• Application Note

Analysis of Local Anesthetics Using XBridge C18

Analysis of Local Anesthetics Using XBridge C18

  • Waters Corporation
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Anesthesia mask and three doctors

This is an Application Brief and does not contain a detailed Experimental section.

Abstract

This application brief highlights analysis of local anesthetics using XBridge C18 Columns.

Introduction

Compounds

Experimental

Test Conditions

Column:

XBridge C18, 5 μm, 4.6 x 150 mm p/n: 186003116

Isocratic Mobile Phase:

10 mM NH4HCO3, pH 10.5/acetonitrile (50:5)

Flow Rate:

1.0 mL/min

Injection Volume:

10 μL

Sample Concentration:

20 μg/mL in water/ACN (50:50)

Temperature:

25 ˚C

Detection:

UV @ 210 nm

Instrument:

Alliance 2695 with 2996 PDA

Results and Discussion

1. Procaine 2. Lidocaine 3. Tetracaine.

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WA60168, April 2007

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