• Application Note

Ranitidine (Symmetry C8) 

Ranitidine (Symmetry C8) 
  • Waters Corporation
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Acid reflux and GERD

This is an Application Brief and does not contain a detailed Experimental section.

Abstract

This application brief highlights the analysis of ranitidine using Symmetry C8 Columns.  

Introduction

Ranitidine was analyzed using Symmetry C8 Columns. 

Ranitidine

Experimental

HPLC Method

Column:

Symmetry C8, 3.9 x 150 mm, 5 μm

Guard column:

Symmetry Guard Column 3.9 x 20 mm, 5 μm

Part numbers:

Column - WAT046970, Guard - WAT054250

Mobile phase:

100 mM sodium acetate, 5mM camphosulfonic acid, pH 6.2/ acetonitrile/methanol 80:10:10

Flow rate:

1.0 mL/min

Injection volume:

5 μL of 100 μg/ml sample

Detection:

UV @ 254 nm

USP Tailing Factor

  1. 1.12 

Results and Discussion

Results

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WA31763.143, June 2003

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