• Application Note

Naltrexone in Serum

Naltrexone in Serum
  • Waters Corporation
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Plasma serum preparation in syringe

This is an Application Brief and does not contain a detailed Experimental section.

Abstract

This application brief highlights the analysis of naltrexone in serum.

Introduction

Compounds used in this application brief includes naloxone (I.S.), and naltrexone.

Experimental

HPLC Conditions

Column:

Symmetry Shield RP8, 3.0 x 150 mm, 5 μm

Guard column:

Sentry guard column, 3.9 x 20 mm, 5 μm

Part numbers:

Column - WAT094243, Guard - WAT200675

Mobile phase:

20 mM ammonium acetate, pH 5/acetonitrile, 90:10

Flow rate:

0.6 mL/min

Injection volume:

20 μL of reconstituted porcine serum extract

Temperature:

25° C

Detection:

UV @ 215 nm

Results and Discussion

Featured Products

WA31763.109, June 2003

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