• Application Note

Drugs of Abuse - LC/UV

Drugs of Abuse - LC/UV
  • Waters Corporation
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Drugs of abuse, mixing of barbiturates and alcohol

For forensic toxicology use only.

This is an Application Brief and does not contain a detailed Experimental section.

Abstract

This application brief demonstrates analysis of drugs of abuse - LC/UV.

Introduction

The compounds used in this study are –

Compounds

USP Tailing

3,4-Methylenedioxyamphetamine (MDA) 

1.08

3,4-Methylenedioxymethamphetamine (MDMA) 

1.32

Alprazolam 

1.18

Flunitrazepam 

1.15

Desmethyidiazepam 

1.14

Diazepam 

1.13

Experimental

Conditions

Column:

Xterra RP18 3.0 x 100 mm, 3.5 μm

Part number:

186000420

Mobile phase A:

5 mM NH4HCO3, pH 9.6

Mobile phase B:

ACN

Flow rate:

0.6 mL/min

Isocratic mobile phase composition:

70% A; 30% B

Injection volume:

10 μL

Sample concentration:

10 ng/μL

Temperature:

40 °C

Detection:

UV @ 210 nm

Instrument:

Alliance 2690, 2996 PDA

Results and Discussion

Featured Products

WA20738.046, June 2002

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