{"id":6691,"date":"2026-05-04T11:30:00","date_gmt":"2026-05-04T11:30:00","guid":{"rendered":"https:\/\/www.waters.com\/blog\/?p=6691"},"modified":"2026-05-07T08:11:14","modified_gmt":"2026-05-07T08:11:14","slug":"identifying-critical-quality-attributes-in-drug-products-your-key-to-ensuring-safe-and-effective-therapeutics","status":"publish","type":"post","link":"https:\/\/www.waters.com\/blog\/identifying-critical-quality-attributes-in-drug-products-your-key-to-ensuring-safe-and-effective-therapeutics\/","title":{"rendered":"Identifying\u00a0Critical Quality Attributes in Drug Products: Your Key to Ensuring Safe and Effective Therapeutics"},"content":{"rendered":"\n<p>In drug manufacturing, there is no room for error. Every decision, from early formulation to final release, must ensure a product is safe, effective, and consistent.<\/p>\n\n\n\n<p>At the center of this process are critical quality attributes (CQAs), the measurable properties that define whether a drug meets its required standards.<br><br>In this blog, we break down the role of CQAs in biologics development and how advanced particle analysis is enabling deeper insight, earlier decisions, and continuity from development through QC.<\/p>\n\n\n<style>.wp-block-kadence-spacer.kt-block-spacer-6691_a07887-8b .kt-block-spacer{height:60px;}.wp-block-kadence-spacer.kt-block-spacer-6691_a07887-8b .kt-divider{border-top-width:1px;height:1px;border-top-color:#eee;width:80%;border-top-style:solid;}<\/style>\n<div class=\"wp-block-kadence-spacer aligncenter kt-block-spacer-6691_a07887-8b\"><div class=\"kt-block-spacer kt-block-spacer-halign-center\"><hr class=\"kt-divider\"\/><\/div><\/div>\n\n\n<style>.wp-block-kadence-advancedheading.kt-adv-heading6691_641f38-b7, .wp-block-kadence-advancedheading.kt-adv-heading6691_641f38-b7[data-kb-block=\"kb-adv-heading6691_641f38-b7\"]{font-style:normal;}.wp-block-kadence-advancedheading.kt-adv-heading6691_641f38-b7 mark.kt-highlight, .wp-block-kadence-advancedheading.kt-adv-heading6691_641f38-b7[data-kb-block=\"kb-adv-heading6691_641f38-b7\"] mark.kt-highlight{font-style:normal;color:#f76a0c;-webkit-box-decoration-break:clone;box-decoration-break:clone;padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;}.wp-block-kadence-advancedheading.kt-adv-heading6691_641f38-b7 img.kb-inline-image, .wp-block-kadence-advancedheading.kt-adv-heading6691_641f38-b7[data-kb-block=\"kb-adv-heading6691_641f38-b7\"] img.kb-inline-image{width:150px;vertical-align:baseline;}<\/style>\n<h2 class=\"kt-adv-heading6691_641f38-b7 wp-block-kadence-advancedheading\" data-kb-block=\"kb-adv-heading6691_641f38-b7\">What are critical quality attributes?<\/h2>\n\n\n\n<p>A CQA is any physical, chemical, biological, or microbiological property that must remain within a defined range to ensure product quality.<\/p>\n\n\n\n<p>CQAs&nbsp;typically fall into three categories:&nbsp;<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Physical characteristics:<\/strong>\u202fthese include aspects such as the size and shape of the pharmaceutical product&nbsp;<\/li>\n\n\n\n<li><strong>Chemical properties:<\/strong>\u202fthese encompass elements like the pH level and concentration of the drug&nbsp;<\/li>\n\n\n\n<li><strong>Biological attributes:<\/strong>\u202fthese involve factors such as sterility and bioburden levels in the product&nbsp;<\/li>\n<\/ul>\n\n\n\n<p>The process of&nbsp;identifying&nbsp;CQAs&nbsp;is an essential step in the drug development process as it ensures that the final drug product is consistent, effective, and safe for patient&nbsp;use.<sup>2<\/sup>\u202fAny deviation can influence the efficacy of a drug, potentially leading to harmful effects on the patient.&nbsp;<\/p>\n\n\n\n<p>Moreover, the recognition of&nbsp;CQAs&nbsp;is not just a best practice;&nbsp;it\u2019s&nbsp;a regulatory mandate. Regulatory authorities, including the FDA and the European Medicines Agency (EMA), require the identification of&nbsp;CQAsas&nbsp;part of the drug&nbsp;development process.<sup>3<\/sup>\u202fThis ensures that drug products meet the necessary quality standards and are safe for consumption.<sup>4<\/sup>&nbsp;<\/p>\n\n\n<style>.wp-block-kadence-spacer.kt-block-spacer-6691_7a9211-f0 .kt-block-spacer{height:60px;}.wp-block-kadence-spacer.kt-block-spacer-6691_7a9211-f0 .kt-divider{border-top-width:1px;height:1px;border-top-color:#eee;width:80%;border-top-style:solid;}<\/style>\n<div class=\"wp-block-kadence-spacer aligncenter kt-block-spacer-6691_7a9211-f0\"><div class=\"kt-block-spacer kt-block-spacer-halign-center\"><hr class=\"kt-divider\"\/><\/div><\/div>\n\n\n<style>.wp-block-kadence-advancedheading.kt-adv-heading6691_65af39-6e, .wp-block-kadence-advancedheading.kt-adv-heading6691_65af39-6e[data-kb-block=\"kb-adv-heading6691_65af39-6e\"]{font-style:normal;}.wp-block-kadence-advancedheading.kt-adv-heading6691_65af39-6e mark.kt-highlight, .wp-block-kadence-advancedheading.kt-adv-heading6691_65af39-6e[data-kb-block=\"kb-adv-heading6691_65af39-6e\"] mark.kt-highlight{font-style:normal;color:#f76a0c;-webkit-box-decoration-break:clone;box-decoration-break:clone;padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;}.wp-block-kadence-advancedheading.kt-adv-heading6691_65af39-6e img.kb-inline-image, .wp-block-kadence-advancedheading.kt-adv-heading6691_65af39-6e[data-kb-block=\"kb-adv-heading6691_65af39-6e\"] img.kb-inline-image{width:150px;vertical-align:baseline;}<\/style>\n<h2 class=\"kt-adv-heading6691_65af39-6e wp-block-kadence-advancedheading\" data-kb-block=\"kb-adv-heading6691_65af39-6e\">CQAs and Quality by Design<\/h2>\n\n\n\n<p>CQAs are foundational to Quality by Design (QbD), a framework that emphasizes building quality into a product from the start, rather than testing for it at the end.<br><br>QbD relies on deep process understanding, identification of risk factors, and control strategies tied directly to CQAs. In practice, this means CQAs must be measured accurately, consistently, and across every stage of development, not just at release.<\/p>\n\n\n<style>.wp-block-kadence-spacer.kt-block-spacer-6691_df75ad-43 .kt-block-spacer{height:60px;}.wp-block-kadence-spacer.kt-block-spacer-6691_df75ad-43 .kt-divider{border-top-width:1px;height:1px;border-top-color:#eee;width:80%;border-top-style:solid;}<\/style>\n<div class=\"wp-block-kadence-spacer aligncenter kt-block-spacer-6691_df75ad-43\"><div class=\"kt-block-spacer kt-block-spacer-halign-center\"><hr class=\"kt-divider\"\/><\/div><\/div>\n\n\n<style>.wp-block-kadence-advancedheading.kt-adv-heading6691_d0392c-94, .wp-block-kadence-advancedheading.kt-adv-heading6691_d0392c-94[data-kb-block=\"kb-adv-heading6691_d0392c-94\"]{font-style:normal;}.wp-block-kadence-advancedheading.kt-adv-heading6691_d0392c-94 mark.kt-highlight, .wp-block-kadence-advancedheading.kt-adv-heading6691_d0392c-94[data-kb-block=\"kb-adv-heading6691_d0392c-94\"] mark.kt-highlight{font-style:normal;color:#f76a0c;-webkit-box-decoration-break:clone;box-decoration-break:clone;padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;}.wp-block-kadence-advancedheading.kt-adv-heading6691_d0392c-94 img.kb-inline-image, .wp-block-kadence-advancedheading.kt-adv-heading6691_d0392c-94[data-kb-block=\"kb-adv-heading6691_d0392c-94\"] img.kb-inline-image{width:150px;vertical-align:baseline;}<\/style>\n<h2 class=\"kt-adv-heading6691_d0392c-94 wp-block-kadence-advancedheading\" data-kb-block=\"kb-adv-heading6691_d0392c-94\">The Challenge: Subvisible Particles as a Critical CQA<\/h2>\n\n\n\n<p>One of the most challenging CQAs in biologics is subvisible particles.<\/p>\n\n\n\n<p>These particles often fall in the \u226510-\u00b5m range and can:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Reduce stability and shorten shelf life<\/li>\n\n\n\n<li>Trigger immune responses or adverse events<\/li>\n<\/ul>\n\n\n\n<p>Because of this, they are closely monitored throughout development and in QC environments. Subvisible particle analysis is also central to meeting compendial requirements, such as USP &lt;788&gt; and USP &lt;789&gt;, which define limits for particulate matter in injectable drug products and set expectations for particle counting and size classification.<\/p>\n\n\n\n<p>Despite their importance, traditional methods have struggled to provide actionable insight, especially in early-stage, low-volume conditions. This creates a gap across the workflow, with limited insight into development, different methods required in QC, and disconnected datasets across the product lifecycle.<\/p>\n\n\n<style>.wp-block-kadence-spacer.kt-block-spacer-6691_794759-52 .kt-block-spacer{height:60px;}.wp-block-kadence-spacer.kt-block-spacer-6691_794759-52 .kt-divider{border-top-width:1px;height:1px;border-top-color:#eee;width:80%;border-top-style:solid;}<\/style>\n<div class=\"wp-block-kadence-spacer aligncenter kt-block-spacer-6691_794759-52\"><div class=\"kt-block-spacer kt-block-spacer-halign-center\"><hr class=\"kt-divider\"\/><\/div><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">Closing the Gap with Advanced Particle Analysis<\/h2>\n\n\n\n<p>The <a href=\"https:\/\/www.waters.com\/nextgen\/us\/en\/products\/particle-analyzers.html\">Aura Particle Analysis System<\/a> addresses this gap by enabling high-resolution particle characterization from development to QC across various therapies \u2013 including biologics, AAVs, LNPs, and cell therapies.<br><br>Using <a href=\"https:\/\/www.waters.com\/nextgen\/us\/en\/applications\/biopharma-and-pharma\/protein-therapies\/particle-counting-and-identification.html\">Backgrounded Membrane Imaging (BMI)<\/a> <a href=\"https:\/\/www.waters.com\/nextgen\/us\/en\/applications\/biopharma-and-pharma\/protein-therapies\/particle-counting-and-identification.html\">and Fluorescence Membrane Microscopy (FMM),<\/a> Aura delivers precise particle count, size distribution, morphology, and particle identification.<br><br>Importantly, Aura supports both:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Small-volume<\/strong> analysis with as little as 5 \u00b5L for early-stage work<\/li>\n\n\n\n<li><strong>Large-volume<\/strong> workflows supporting over 500 \u00b5L per sample to align with QC expectations<\/li>\n<\/ul>\n\n\n\n<p>This allows teams to generate meaningful CQA data earlier, maintain one method across stages, and build a continuous dataset from formulation through release.<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img decoding=\"async\" width=\"903\" height=\"405\" src=\"https:\/\/www.waters.com\/blog\/wp-content\/uploads\/image-23.png\" alt=\"Graph showing Fluor 2 intensity by Diameter (ECD). Reveal particle size and count distribution with BMI and FMM.\" class=\"wp-image-6695\" srcset=\"https:\/\/www.waters.com\/blog\/wp-content\/uploads\/image-23.png 903w, https:\/\/www.waters.com\/blog\/wp-content\/uploads\/image-23-300x135.png 300w, https:\/\/www.waters.com\/blog\/wp-content\/uploads\/image-23-768x344.png 768w\" sizes=\"(max-width: 903px) 100vw, 903px\" \/><figcaption class=\"wp-element-caption\">Reveal particle size and count distribution with&nbsp;BMI&nbsp;and&nbsp;FMM.<\/figcaption><\/figure>\n<\/div>\n\n<style>.wp-block-kadence-spacer.kt-block-spacer-6691_9ee7bd-6d .kt-block-spacer{height:60px;}.wp-block-kadence-spacer.kt-block-spacer-6691_9ee7bd-6d .kt-divider{border-top-width:1px;height:1px;border-top-color:#eee;width:80%;border-top-style:solid;}<\/style>\n<div class=\"wp-block-kadence-spacer aligncenter kt-block-spacer-6691_9ee7bd-6d\"><div class=\"kt-block-spacer kt-block-spacer-halign-center\"><hr class=\"kt-divider\"\/><\/div><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">A More Complete View of CQAs<\/h2>\n\n\n\n<p>By providing deeper visibility into subvisible particles, one of the most complex CQAs, the Aura System enables earlier detection of instability or aggregation, better differentiation between particle types, and more informed decision-making throughout development.<\/p>\n\n\n\n<p>Instead of reacting to CQA failures late, teams can design around them from the start.<\/p>\n\n\n<style>.wp-block-kadence-spacer.kt-block-spacer-6691_959a25-b6 .kt-block-spacer{height:60px;}.wp-block-kadence-spacer.kt-block-spacer-6691_959a25-b6 .kt-divider{border-top-width:1px;height:1px;border-top-color:#eee;width:80%;border-top-style:solid;}<\/style>\n<div class=\"wp-block-kadence-spacer aligncenter kt-block-spacer-6691_959a25-b6\"><div class=\"kt-block-spacer kt-block-spacer-halign-center\"><hr class=\"kt-divider\"\/><\/div><\/div>\n\n\n<style>.wp-block-kadence-advancedheading.kt-adv-heading6691_bfed4d-8d, .wp-block-kadence-advancedheading.kt-adv-heading6691_bfed4d-8d[data-kb-block=\"kb-adv-heading6691_bfed4d-8d\"]{font-style:normal;}.wp-block-kadence-advancedheading.kt-adv-heading6691_bfed4d-8d mark.kt-highlight, .wp-block-kadence-advancedheading.kt-adv-heading6691_bfed4d-8d[data-kb-block=\"kb-adv-heading6691_bfed4d-8d\"] mark.kt-highlight{font-style:normal;color:#f76a0c;-webkit-box-decoration-break:clone;box-decoration-break:clone;padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;}.wp-block-kadence-advancedheading.kt-adv-heading6691_bfed4d-8d img.kb-inline-image, .wp-block-kadence-advancedheading.kt-adv-heading6691_bfed4d-8d[data-kb-block=\"kb-adv-heading6691_bfed4d-8d\"] img.kb-inline-image{width:150px;vertical-align:baseline;}<\/style>\n<h2 class=\"kt-adv-heading6691_bfed4d-8d wp-block-kadence-advancedheading\" data-kb-block=\"kb-adv-heading6691_bfed4d-8d\">Conclusion<\/h2>\n\n\n\n<p>CQAs are the foundation of drug quality, but their value depends on how well they are understood and controlled.<\/p>\n\n\n\n<p>As biologics grow more complex, the need for technologies that can deliver accurate, consistent, and stage-spanning insight continues to increase.<\/p>\n\n\n\n<p>With advanced particle analysis, it is now possible to move from fragmented workflows to a single, continuous understanding of CQAs across the development process.<\/p>\n\n\n<style>.wp-block-kadence-spacer.kt-block-spacer-6691_2b0d43-ee .kt-block-spacer{height:60px;}.wp-block-kadence-spacer.kt-block-spacer-6691_2b0d43-ee .kt-divider{border-top-width:1px;height:1px;border-top-color:#eee;width:80%;border-top-style:solid;}<\/style>\n<div class=\"wp-block-kadence-spacer aligncenter kt-block-spacer-6691_2b0d43-ee\"><div class=\"kt-block-spacer kt-block-spacer-halign-center\"><hr class=\"kt-divider\"\/><\/div><\/div>\n\n\n<style>.wp-block-kadence-advancedheading.kt-adv-heading6691_a5488c-60, .wp-block-kadence-advancedheading.kt-adv-heading6691_a5488c-60[data-kb-block=\"kb-adv-heading6691_a5488c-60\"]{font-style:normal;}.wp-block-kadence-advancedheading.kt-adv-heading6691_a5488c-60 mark.kt-highlight, .wp-block-kadence-advancedheading.kt-adv-heading6691_a5488c-60[data-kb-block=\"kb-adv-heading6691_a5488c-60\"] mark.kt-highlight{font-style:normal;color:#f76a0c;-webkit-box-decoration-break:clone;box-decoration-break:clone;padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;}.wp-block-kadence-advancedheading.kt-adv-heading6691_a5488c-60 img.kb-inline-image, .wp-block-kadence-advancedheading.kt-adv-heading6691_a5488c-60[data-kb-block=\"kb-adv-heading6691_a5488c-60\"] img.kb-inline-image{width:150px;vertical-align:baseline;}<\/style>\n<h2 class=\"kt-adv-heading6691_a5488c-60 wp-block-kadence-advancedheading\" data-kb-block=\"kb-adv-heading6691_a5488c-60\">References<\/h2>\n\n\n\n<ol start=\"1\" class=\"wp-block-list\">\n<li><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4070262\/#CR3\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4070262\/#CR3<\/a>&nbsp;<\/li>\n<\/ol>\n\n\n\n<ol start=\"2\" class=\"wp-block-list\">\n<li><a href=\"https:\/\/www.linkedin.com\/pulse\/benefits-identifying-critical-quality-attributes-cqas-mo-heidaran-2e\/\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/www.linkedin.com\/pulse\/benefits-identifying-critical-quality-attributes-cqas-mo-heidaran-2e\/<\/a>&nbsp;<\/li>\n<\/ol>\n\n\n\n<ol start=\"3\" class=\"wp-block-list\">\n<li>S. Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research (CDER). Guidance for Industry: Q8(R2) Pharmaceutical Development. November 2009.&nbsp;<\/li>\n<\/ol>\n\n\n\n<ol start=\"4\" class=\"wp-block-list\">\n<li><a href=\"https:\/\/www.roosterbio.com\/blog\/critical-quality-attributes-cqas-know-their-importance-limitations-in-product-process-development\/\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/www.roosterbio.com\/blog\/critical-quality-attributes-cqas-know-their-importance-limitations-in-product-process-development\/<\/a>&nbsp;<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>In drug manufacturing, there is no room for error. Every decision, from early formulation to final release, must ensure a product is safe, effective, and consistent. At the center of this process are critical quality attributes (CQAs), the measurable properties that define whether a drug meets its required standards. In this blog, we break down&#8230;<\/p>\n","protected":false},"author":139,"featured_media":6694,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_seopress_robots_primary_cat":"none","_seopress_titles_title":"%%post_title%% %%sep%% %%sitetitle%%","_seopress_titles_desc":"Learn about critical quality attributes, their role in drug development, and how cutting-edge\u00a0particle analysis technology helps identify\u00a0and\u00a0analyze\u00a0CQAs.\u00a0","_seopress_robots_index":"","_seopress_analysis_target_kw":"cqas,critical quality attributes,quality by design,cqas in drug products,critical quality attributes in drug products","_kad_blocks_custom_css":"","_kad_blocks_head_custom_js":"","_kad_blocks_body_custom_js":"","_kad_blocks_footer_custom_js":"","_kad_post_transparent":"","_kad_post_title":"","_kad_post_layout":"","_kad_post_sidebar_id":"","_kad_post_content_style":"","_kad_post_vertical_padding":"","_kad_post_feature":"","_kad_post_feature_position":"","_kad_post_header":false,"_kad_post_footer":false,"_kad_post_classname":"","footnotes":""},"categories":[228,1],"tags":[533,51,52,734,735,624],"class_list":["post-6691","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-biopharmaceutical","category-general","tag-aqbd","tag-biopharma","tag-biopharmaceutical","tag-cqas","tag-critical-quality-attributes","tag-quality-control"],"acf":[],"taxonomy_info":{"category":[{"value":228,"label":"Biopharmaceutical"},{"value":1,"label":"General"}],"post_tag":[{"value":533,"label":"AQbD"},{"value":51,"label":"biopharma"},{"value":52,"label":"biopharmaceutical"},{"value":734,"label":"cqas"},{"value":735,"label":"critical quality attributes"},{"value":624,"label":"quality control"}]},"featured_image_src_large":["https:\/\/www.waters.com\/blog\/wp-content\/uploads\/image-22.png",600,342,false],"author_info":{"display_name":"Waters Staff","author_link":"https:\/\/www.waters.com\/blog\/author\/waters_staff\/"},"comment_info":"","category_info":[{"term_id":228,"name":"Biopharmaceutical","slug":"biopharmaceutical","term_group":0,"term_taxonomy_id":228,"taxonomy":"category","description":"We help ensure the medicines people take every day are reliably safe and effective, from the common aspirin to the most complex biotherapy. Tests performed using our liquid chromatography-mass spectrometry (LC-MS) instruments ensure the efficacy and safety of these complex, protein-based drugs well before they reach the patient.","parent":25,"count":42,"filter":"raw","term_order":"0","cat_ID":228,"category_count":42,"category_description":"We help ensure the medicines people take every day are reliably safe and effective, from the common aspirin to the most complex biotherapy. Tests performed using our liquid chromatography-mass spectrometry (LC-MS) instruments ensure the efficacy and safety of these complex, protein-based drugs well before they reach the patient.","cat_name":"Biopharmaceutical","category_nicename":"biopharmaceutical","category_parent":25},{"term_id":1,"name":"General","slug":"general","term_group":0,"term_taxonomy_id":1,"taxonomy":"category","description":"","parent":0,"count":52,"filter":"raw","term_order":"0","cat_ID":1,"category_count":52,"category_description":"","cat_name":"General","category_nicename":"general","category_parent":0}],"tag_info":[{"term_id":533,"name":"AQbD","slug":"aqbd","term_group":0,"term_taxonomy_id":533,"taxonomy":"post_tag","description":"","parent":0,"count":2,"filter":"raw","term_order":"0"},{"term_id":51,"name":"biopharma","slug":"biopharma","term_group":0,"term_taxonomy_id":51,"taxonomy":"post_tag","description":"","parent":0,"count":50,"filter":"raw","term_order":"0"},{"term_id":52,"name":"biopharmaceutical","slug":"biopharmaceutical","term_group":0,"term_taxonomy_id":52,"taxonomy":"post_tag","description":"","parent":0,"count":59,"filter":"raw","term_order":"0"},{"term_id":734,"name":"cqas","slug":"cqas","term_group":0,"term_taxonomy_id":734,"taxonomy":"post_tag","description":"","parent":0,"count":1,"filter":"raw","term_order":"0"},{"term_id":735,"name":"critical quality attributes","slug":"critical-quality-attributes","term_group":0,"term_taxonomy_id":735,"taxonomy":"post_tag","description":"","parent":0,"count":1,"filter":"raw","term_order":"0"},{"term_id":624,"name":"quality control","slug":"quality-control","term_group":0,"term_taxonomy_id":624,"taxonomy":"post_tag","description":"","parent":0,"count":2,"filter":"raw","term_order":"0"}],"_links":{"self":[{"href":"https:\/\/www.waters.com\/blog\/wp-json\/wp\/v2\/posts\/6691","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.waters.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.waters.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.waters.com\/blog\/wp-json\/wp\/v2\/users\/139"}],"replies":[{"embeddable":true,"href":"https:\/\/www.waters.com\/blog\/wp-json\/wp\/v2\/comments?post=6691"}],"version-history":[{"count":0,"href":"https:\/\/www.waters.com\/blog\/wp-json\/wp\/v2\/posts\/6691\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.waters.com\/blog\/wp-json\/wp\/v2\/media\/6694"}],"wp:attachment":[{"href":"https:\/\/www.waters.com\/blog\/wp-json\/wp\/v2\/media?parent=6691"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.waters.com\/blog\/wp-json\/wp\/v2\/categories?post=6691"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.waters.com\/blog\/wp-json\/wp\/v2\/tags?post=6691"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}