Waters single and tandem quadrupole systems have set the standard for forensic toxicology screening applications in forensic laboratories over many years. The ACQUITY QDa and Xevo TQ-S micro now provide exceptional performance combined with ease of use in compact and robust designs. Whether you need to identify seized drugs or detect and identify toxicants in physiological fluids, Waters can provide a high performance, compact, and accessible solution for your laboratory.
Waters MS and MS/MS forensic toxicology screening systems provide:
Seized Drug Analysis Using the ACQUITY QDa Mass Detector
The ACQUITY QDa Mass Detector enables seized drug analysis using either an LC inlet or direct analysis with a DART ionization source. With the ACQUITY QDa, seized drug analysis can be performed without the time consuming sample derivatization and preparation of GC-MS methods, enabling laboratories to improve throughput and simplify workflows. ACQUITY QDa is as intuitive as an optical detector with the robustness to handle all of your analyses. Working in harmony with liquid chromatography or a DART ionization source, it is ideally suited for seized drug analysis.
The ACQUITY UPLC I-Class coupled with Xevo TQD or Xevo TQ-S micro are the latest generation of Waters UPLC-MS/MS systems and offer improved chromatography, faster data acquisition, and increased functionality to improve your forensic toxicology screening capabilities.
Whether your need is to detect and identify commonly detected compounds or perform a broad comprehensive screen or perform accurate quantitative analysis, the Xevo TQD and Xevo TQ-S micro systems offer exceptional performance, robustness, and ease-of- use in a compact space saving design. The Xevo TQD and Xevo TQ-S micro can also be used for a wide range of quantitative or confirmation assay.
Automatic Data Processing
Automatic data processing enables quick and easy data review using Waters ChromaLynx and TargetLynx application managers. Specific application managers are provided to automatically process the acquired MS data for both MRM and full scan MS methods. Data is presented in easy-to-view browsers showing identified components and the criteria used for the identification.
High Sensitivity MRM and Comprehensive Full Scan MS Methods on the Same System
Two complementary screening methods, which utilize the same chromatography and can be run on the same system, allow you to detect and identify a wide variety of compounds encountered in forensic toxicology investigations. You can either run a high sensitivity MRM method or take advantage of a full scan MS method to search against a library of over 950 compounds. Alternatively, you can run both methods to provide the most comprehensive analysis of your sample.
The Waters library, used with the full scan MS screening method, has been developed in collaboration with leading forensic toxicology laboratories and can be easily updated by the user. The library includes over 950 compounds with both mass spectrometry and retention time data. These compounds include illicit drugs, prescription drugs, over-the-counter (OTC) drugs, pesticides, and psychoactive substances.
Both MRM and full scan methods are supplied on a DVD to ensure you are up and running quickly. You will not have to spend valuable time developing chromatography methods or optimising Mass spectrometry parameters. Preconfigured chromatography, MS acquisition and data processing parameters required to perform a targeted or broad comprehensive screening analysis on the Xevo TQD/Xevo TQ-S micro platforms are available.
Webinar: Targeted, Semi-targeted and Non-targeted Screening Approaches Using UPLC/QTof Technology with the UNIFI Scientific Information System for Forensic Toxicology Analysis
Forensic Toxicology Screening Application Solution with UNIFI
Forensic Toxicology Video Library
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View Forensic Toxicology Application Notes
UPLC (/MS) Application Note Browser
Forensic Toxicology Application Notebook