Since 2003, Waters has developed innovative stationary phases for Hydrophilic Interaction Chromatography [HILIC] to overcome the challenge of retaining and separating extremely polar compounds. In addition to enhanced retention of polar compounds, ACQUITY UPLC® BEH, XBridge™ and Atlantis® HILIC columns provide increased mass spectrometry response, direct compatibility with sample preparation eluates [PPT, LLE and SPE] as well as orthogonal selectivity compared to RP materials, making HILIC an attractive alternative separation technique.

Click below to explore the benefits of Waters HILIC columns.

link to env catalog link to application note