Waters: Analytical & Preparative Columns

Analytical Columns

Waters is on the forefront of modern HPLC & UPLC^®column technology. Our industry-leading columns eliminate significant time and cost per sample from your analytical process—while improving the quality of laboratory results.

As one of the world’s few primary column manufacturers, our ability to control column to column reproducibility, as well as produce some of the most innovative new chemistries, is second to none in the industry.

Particle Technology
USP L Listings
Separation Modes

	ACQUITY UPLC Columns The most technologically advanced LC columns ever created. Designed, tested, and guaranteed for use in applications up to 15000 psi (1000 bar), they provide unsurpassed efficiency, ruggedness and throughput. Combine faster separations with higher resolution by harnessing the full potential of small particles.
	XSelect Columns The proprietary Charged Surface Hybrid (CSH) Technology that powers XSelect columns redefines the selectivity map for method developers and offers the highest performance for basic compounds in the acidic, low ionic strength mobile phases commonly used in LC/MS laboratories. CSH Technology was engineered to offer low column bleed, excellent batch-to-batch reproducibility and transferability between particle sizes and column formats.
	XBridge Columns With an order-of-magnitude improvement in high pH stability and a higher level of chromatographic performance, Ethylene Bridged Hybrid (BEH) columns define the new benchmark for LC method development with excellent stability over a wide pH range (1-12).
	Atlantis Columns The industry standard for polar compound retention for reversed-phase and HILIC separations.
	SunFire Columns With the state-of-the-art reversed-phase C₁₈ and C₈ bonding and endcapping technology, these columns provide best peak shape for basic compounds, excellent low pH stability, high efficiency, and greater mass loading capacity.
	XTerra Columns Based on the first generation of Hybrid Particle technology, these columns deliver sharp symmetrical peaks for basic compounds over a mobile phase pH range of 2-12.
	Symmetry Columns Sets the standard for reproducibility for HPLC drug assays, giving you confidence in the long term compliance of your HPLC methods.
	YMC Columns A wide choice of HPLC columns with a range of selectivity that help you succeed in developing robust separations. Supported by over 400 applications.
	Other Analytical Columns Additional products in our column portfolio include: Spherisorb, µBondapal/Bondapak, Nova-Pak, Resolve, PAH, µPorasil/Porasil, RSPak, column accessories, application-specific columns and products, and bioseparation columns.

Preparative Columns

Waters changed the purification landscape with its Optimum Bed Density (OBD™) columns. With customers consistently achieving over 3,000 injections per column, these columns help increase productivity and save money. More than 10,000 OBD columns have shipped without a single bed failure due to voiding. Laboratories worldwide rely on the high purity and recovery achieved with these premier preparative column brands.

OBD Technology
Particle Technology
Separation Modes

	XSelect Prep OBD Columns Charged Surface Hybrid (CSH) Technology-powered preparative columns feature high-mass loading capacity for basic compounds and the ability to seamlessly scale separations between UPLC, analytical HPLC and preparative HPLC platforms. The seamless scalability built into CSH Technology columns permits the use of UPLC as a powerful method development tool for the isolation and purification scientist.
	XBridge Prep OBD Columns BEH Technology™ (Ethylene Bridged Hybrid) particles offer flexibility with new levels of low and high pH stability for fast purification method development. Wide pH operating range and high loadability provide reliable solutions for the most challenging purification requirements.
	Atlantis Prep OBD Columns The industry standard for polar compound retention and purification. Available for reversed-phase and HILIC chromatography modes, these columns exhibit significantly greater retention compared to conventional C₁₈or embedded polar group column chemistries.
	SunFire Prep OBD Columns By combining new bonding and endcapping technologies, SunFire™ Prep columns offer superior performance, long column lifetimes, and the highest mass loading capacity for basic molecules.
	Peptide Separation Technology Prep OBD Columns Tested with a peptide standard mixture for consistent, predictable batch-to-batch and column-to-column performance, these columns isolate peptides of differing size, hydrophobicity, and isoelectric point.
	XTerra Prep Columns Analytical performance in prep dimensions with maximum column stability. Provide unprecedented flexibility, both through the range of analytes—basic, acidic and polar—and the wide operating range of mobile phases.
	YMC Prep Columns High Performance Prep columns, available in YMC*Gel and select YMC Pro C₁₈packings, for successful, predictable preparative scale-up.
	Other Prep Columns Additional products in our preparative column portfolio include: SymmetryPrep, Spherisorb, Bondapak, Porasil silica packing material, and a wide selection of radial compression column segments.

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Analytical & Preparative Columns

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