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MS Upgrades

Waters offers a range of MS hardware upgrades and sample inlet options that will improve your system's control and data acquisition functions, as well as increase its analytical capabilities and extend its operational lifetime.

To find out about the full range of MS field upgrades, sources, and probes available for a specific instrument type, please use the upgrade selector tool below:

Alternately, select from one of the more popular upgrade products below.


Upgrade your SYNAPT™ MS or SYNAPT G2 MS to full HDMS™ capability to benefit from high efficiency ion mobility separations enabling you to differentiate samples based on size, shape, charge, and mass.
Q-Tof Premier™, SYNAPT MS/HDMS™ and SYNAPT G2 MS/HDMS instruments upgraded with a MALDI source system provide the uncompromised exact mass characterization of compounds using MALDI-MS, MALDI-MS/MS, and MALDI-MS/IMS/MS (HDMS only) analyses.
The NanoLockSpray™ dual electrospray ion source accessory with optimized co-introduction of analyte and lock mass compounds provides authenticated exact mass measurement in NanoFlow™ LC/MS and LC/MS/MS modes of operation.
The Atmospheric Pressure GC (APGC) source field upgrade allows laboratories to extend the capabilities of their LC/MS analytical instrumentation, by incorporating the ability to perform AP GC/MS on a single MS platform.
The Atmospheric Pressure Photoionization (APPI) source, in conjunction with Atmospheric Pressure Chemical Ionization (APCI), allows independent APPI and APCI experiments with the ability to acquire APPI and APCI data in the same analysis.
The Atmospheric Solids Analysis Probe is a useful tool for the rapid direct analysis of volatile and semi-volatile solid and liquid samples using atmospheric pressure ionisation.
Provides a clean, dry, and lubricant-free vacuum and environmentally superior alternative to the standard oil-sealed rotary vacuum pump. ALSO AVAILABLE FOR Quattro Premier™/XE AND Quattro micro™ API
APCI is an effective method for analyzing lower-polarity compounds. The high-efficiency IonSABRE™ APCI probe offers significant improvements in sensitivity compared with earlier versions of probe, particularly at higher liquid flow rates.
Enables MS methods to be developed that use both ESI and APCI in the same analysis by combining high-speed switching within the ion source.
Combines the existing functionality of the ESCi® multi-mode ionization source with the LockSpray™ interface to provide ESCi exact mass data acquisition capabilities.
The Embedded PC Acquisition System (EPCAS™) Conversion Program for your Q-Tof™ 2 Mass Spectrometer helps preserve your initial MS investment by prolonging the instrument’s lifetime, improving its analytical capabilities, and enhancing its ease of use.
The LockSpray™ dual electrospray ion source optimizes the co-introduction of analyte and lock mass compound directly into the ion source, providing authenticated exact mass measurement in MS and MS/MS modes.
Increase the analytical capabilities and productivity of your MALDI Q-Tof Premier™ Mass Spectrometer by upgrading the present laser to a high repetition rate solid state laser system, providing improved reliability and reduced servicing demands.
Enables instruments configured with an IonSABRE™ probe and LockSpray™ interface to acquire APCI and ESCi® exact mass data.
Increase the analytical capabilities of your GCT Premier™ Mass Spectrometer by adding the dual purpose, ‘soft’ ionization, Field Desorption/Field Ionization (FD/FI) source, which provides abundant molecular ions from a wide range of compounds.
Direct Insertion (DI)/Desorption Chemical Ionization (DCI) probes provide an effective method for the analysis of relatively non-volatile samples by Electron Impact/Chemical Ionization, with DCI preferred for more thermally labile samples.

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