Literature


Description
Single Digit Reproducibility Using ProteinWorks eXpress Digest Kits
Library Number: APNT134874203 | Format: PDF | File Size: 517.26 kB | Year: 2016 | Content Type: Application Notes

To demonstrate the high reproducibility of ProteinWorks™ eXpress Digest Kits resulting from a standardized protocol and pre-weighed, lot-traceable reagents.

LC-MS Quantification of Trastuzumab Using Pellet Digestion and ProteinWorks eXpress Direct Digest Ki...
Library Number: APNT134874215 | Format: PDF | File Size: 940.45 kB | Year: 2016 | Content Type: Application Notes

LC-MS Quantification of Trastuzumab Using Pellet Digestion and ProteinWorks eXpress Direct Digest Kits

Antibody Quantification Using ProteinWorks eXpress Digest Kits
Library Number: APNT134874212 | Format: PDF | File Size: 753.15 kB | Year: 2016 | Content Type: Application Notes

To demonstrate the broad applicability across a range of sample volumes, and the inherent flexibility of the ProteinWorks™ eXpress Direct Digest Kits for the quantification of monoclonal antibody (mAb) drugs by LC-MS/MS.

A Universal, Optimized SPE Protocol for Clean-up of Tryptic Peptides in Protein Bioanalysis
Library Number: APNT134868364 | Format: PDF | File Size: 1519.67 kB | Year: 2015 | Content Type: Application Notes

This technology brief demonstrates the performance of an optimized method for tryptic peptide clean-up in protein bioanalysis.

Using Hydrophilic Interaction Chromatography for Heightened Product Characterization to Overcome Cha...
Library Number: APNT134888711 | Format: PDF | File Size: 1456.4 kB | Year: 2016 | Content Type: Application Notes

This application note describes chromatographic recovery of hydrophobic mAb and antibody drug conjugate (ADC) subunits.

Screening Workflow for Extractables Testing Using the UNIFI Scientific Information System
Library Number: APNT134888897 | Format: PDF | File Size: 2024.23 kB | Year: 2016 | Content Type: Application Notes

This technical note describes a simple workflow and methodology for the screening and characterization of cosmetics, 3D printing media, food, and pharmaceutical packaging extractable applications.

A Fast Efficient Method to Determine the Presence of Nitrosamines in Cosmetics, Personal Care, and C...
Library Number: APNT134888543 | Format: PDF | File Size: 1603.07 kB | Year: 2016 | Content Type: Application Notes

In this application note, we describe the analysis of eight volatile and non-volatile N-nitrosamines previously detected in cosmetics and personal care formulations using the ACQUITY I-Class System and Xevo TQ-S micro.

High Sensitivity Quantification of Infliximab in Rat Plasma Using a Fast, Standardized Kit-Based App...
Library Number: APNT134868864 | Format: PDF | File Size: 1300.26 kB | Year: 2016 | Content Type: Application Notes

This application note describes the fast, sensitive quantification of infliximab from rat plasma using the ProteinWorks eXpress Digest Kit and Protocol.

A Generic Kit-Based Approach for Quantifying Monoclonal Antibody Drugs Through Direct Digestion of D...
Library Number: APNT134873397 | Format: PDF | File Size: 1336.76 kB | Year: 2016 | Content Type: Application Notes

In this application note, we have used the ProteinWorks™ eXpress Direct Digest Kit to simplify and streamline the workflow process using the same universal protocol and reagents for all monoclonal antibody drugs tested.

The Determination of Sucralose in Flavored Waters using CORTECS 2.7 μm C18 Chemistry and Refractive ...
Library Number: APNT134888314 | Format: PDF | File Size: 722.58 kB | Year: 2016 | Content Type: Application Notes

This technical brief describes the analysis of sucralose in flavored waters utilizing a simple isocratic separation.

Untargeted Metabolomics and Lipidomics Application Notebook
Library Number: APNT134843697 | Format: PDF | File Size: 6416.8 kB | Year: 2015 | Content Type: Application Notes

In this notebook, we cover untargeted metabolomics and lipidomics applications with Waters solutions.

Targeted Metabolomics and Lipidomics Application Notebook
Library Number: APNT134843707 | Format: PDF | File Size: 5431.42 kB | Year: 2015 | Content Type: Application Notes

In this notebook, we cover targeted metabolomics and lipidomics applications with Waters solutions.

UHPLC Analysis of a Pesticide Formulation Using the ACQUITY Arc System with PDA, Mass Detection, and...
Library Number: APNT134888231 | Format: PDF | File Size: 974.31 kB | Year: 2016 | Content Type: Application Notes

In this application note, we present the analysis of a commercially available pesticide formulation which contained two active ingredients (AI): an insecticide AI 1, and tebuconazole, a triazole fungicide, AI 2.

Quantification of 1,25-Dihydroxyvitamin D2 and D3 From Human Serum Using Immunopurification, ACQUITY...
Library Number: APNT134888116 | Format: PDF | File Size: 924.1 kB | Year: 2016 | Content Type: Application Notes

In this application note quantification of 1,25-Dihydroxyvitamin D2 and D3 was studied.

An Improved Workflow for DESI Imaging Mass Spectrometry Incorporating Waters High Definition Imaging...
Library Number: APNT134887440 | Format: PDF | File Size: 1468.41 kB | Year: 2016 | Content Type: Application Notes

This technology brief describes a new software acquisition approach which streamlines DESI imaging workflow to maximize data acquisition.

Metabolomics & Lipidomics Application Notebook
Library Number: APNT134841740 | Format: PDF | File Size: 12074.22 kB | Year: 2015 | Content Type: Application Notes

In this notebook, we cover applications with Waters solutions for metabolomics and lipidomics, including untargeted and targeted analyses, structural elucidation, MS imaging, and ambient ionization-MS applications.

Performance Comparison of a Scaled USP Method for Fluconazole Using ACQUITY UPLC and Competitive UHP...
Library Number: APNT134875726 | Format: PDF | File Size: 753.5 kB | Year: 2016 | Content Type: Application Notes

This application note details the ability to scale traditional HPLC methods to modern UPLC methods providing equivalent or enhanced performance while decreasing run time and solvent consumption.

Structural Elucidation Application Notebook
Library Number: APNT134843702 | Format: PDF | File Size: 4726.98 kB | Year: 2015 | Content Type: Application Notes

In this notebook, we cover structural elucidation applications with Waters solutions. This notebook is an excerpt from the lager Waters' Application Notebook on Metabolomics and Lipidomics, P/N 720005245EN.

MS Imaging and Ambient Ionization-MS for Metabolomics and Lipidomics Application Notebook
Library Number: APNT134843712 | Format: PDF | File Size: 6115.96 kB | Year: 2015 | Content Type: Application Notes

In this notebook, we cover MS imaging and ambient ionization-MS application for metabolomics and lipidomics with Waters solutions.

USP Method Modernization Using “Equivalent L/dp” and “Equivalent N” Allowed Changes with CORTECS C8 ...
Library Number: APNT134886223 | Format: PDF | File Size: 1127.08 kB | Year: 2016 | Content Type: Application Notes

This application note illustrates how an analyst can use solid-core CORTECS Columns to modernize a USP method.

A Label-free, Data-independent Approach to Defining the Gluten Proteome
Library Number: APNT134886216 | Format: PDF | File Size: 957.28 kB | Year: 2016 | Content Type: Application Notes

This study highlights improved gluten extraction efficiency using RapiGest followed by label-free LC-HDMSE (LC-DIA-IM-MS) approach.

A Label-Free, Multi-Omic Study to Qualitatively and Quantitatively Characterize the Effects of a Glu...
Library Number: APNT134808146 | Format: PDF | File Size: 3974.24 kB | Year: 2014 | Content Type: Application Notes

A label-free, multi-omics approach provided qualitative and quantitative information in a single experiment to help characterize and investigate the effects of a glucosylceramide inhibitor for treatment of obesity.

Multi-Residue Pesticide Screening for Dried Botanicals
Library Number: APNT134885296 | Format: PDF | File Size: 2955.22 kB | Year: 2016 | Content Type: Application Notes

In this technology brief, learn how the Xevo TQ-S micro and APGC enables multi-residue pesticide analyses for both LC and GC amenable compounds on a single MS system.

UPLC-MS/MS Analysis of Azole Antifungals in Serum for Clinical Research
Library Number: APNT134885251 | Format: PDF | File Size: 1251.99 kB | Year: 2016 | Content Type: Application Notes

The analysis of Azole antifungals in serum was described in this application note.

Quantitation of High Resolution MS Data Using UNIFI: Acquiring and Processing Full Scan or Tof-MRM (...
Library Number: APNT134885232 | Format: PDF | File Size: 1557.49 kB | Year: 2016 | Content Type: Application Notes

This application note enables the user to collect HRMS data for quantitation, set up a simple quantitative processing method, and review the results within UNIFI.