Order Center

Literature


Description
Waters Environmental Application Notes Booklet
Library Number: APNT134807775 | Format: PDF | File Size: 8268.62 kB | Year: 2014 | Content Type: Application Notes

In our 2014 environmental application notes booklet, learn how Waters latest technologies are being applied to the analysis of dioxins, perfluoroalkyl and polyfluoroalkyl substances (PFAS’s), Polycyclic aromatic hydrocarbons (PAHs), pharmaceuticals and...

Future-proofing the Biopharmaceutical QC Laboratory: Using the ACQUITY UPLC H-Class Bio to Run SEC H...
Library Number: APNT134807673 | Format: PDF | File Size: 1818.76 kB | Year: 2014 | Content Type: Application Notes

To demonstrate the applicability of the ACQUITY UPLC H-Class Bio System for performing both SEC-HPLC and SEC-UPLC, we present here the transfer of an SEC-HPLC assay for monoclonal antibody aggregation from legacy HPLC instrumentation to the ACQUITY UPLC H...

Rapid and Simultaneous Analysis of Plasma Catecholamines and Metanephrines Using Mixed-Mode SPE and ...
Library Number: APNT134807281 | Format: PDF | File Size: 1659.94 kB | Year: 2014 | Content Type: Application Notes

The extraction and analysis of plasma catecholamines and metanephrines using Oasis WCX μElution Plates and an ACQUITY UPLC BEH Amide Column in HILIC mode is detailed.

Rapid and Simultaneous Analysis of Urinary Catecholamines and Metanephrines Using Mixed-Mode SPE and...
Library Number: APNT134807288 | Format: PDF | File Size: 1480.77 kB | Year: 2014 | Content Type: Application Notes

The extraction and analysis of urinary catecholamines and metanephrines using the Oasis mixed-mode weak cation exchange (WCX) plates and an ACQUITY UPLC BEH Amide

Clinical Research Method for the Fast, Efficient Analysis of Mycophenolic Acid Utilizing Online Soli...
Library Number: APNT134738817 | Format: PDF | File Size: 2257.83 kB | Year: 2014 | Content Type: Application Notes

In this study, an automated method for efficiently and accurately measuring mycophenolic acid from plasma has been developed.

Forced Degradation Analysis of Omeprazole Using CORTECS 2.7 μm Columns
Library Number: APNT134806927 | Format: PDF | File Size: 1440.18 kB | Year: 2014 | Content Type: Application Notes

In this application note a forced degradation study of Omeprazole was performed using a CORTECS C18+, 2.7 μm, 4.6 x 150 mm Column on an Alliance HPLC System equipped with both a PDA and QDa Detector.

Transferring HPLC Gradient Methods Using CORTECS Solid-Core Particle Columns
Library Number: APNT134806971 | Format: PDF | File Size: 1516.9 kB | Year: 2014 | Content Type: Application Notes

The following application note demonstrates a proper method transfer of a typical HPLC gradient method for abacavir-related compounds.

Selective and Sensitive Screening of 23 Azo Dyes Using the ACQUITY UPLC H-Class System and the ACQUI...
Library Number: APNT134806029 | Format: PDF | File Size: 631.89 kB | Year: 2014 | Content Type: Application Notes

This technology brief descrives a rapid, easy, and selective quantification method for prohibited azo dyes at 100 times below the legislative limits.

LC-MS Determination of Sudan Dyes in Chili Oleoresin Using the CORTECS C18, 2.7 μm Column
Library Number: APNT134805553 | Format: PDF | File Size: 1754.82 kB | Year: 2014 | Content Type: Application Notes

This application note presents an SPE-based analytical method suitable for the determination of common Sudan dyes in chili oleoresin.

Performance Stability of CORTECS 2.7 μm Columns Following Repeated Injections of Precipitated Plasma
Library Number: APNT134805602 | Format: PDF | File Size: 1107.82 kB | Year: 2014 | Content Type: Application Notes

This technical note details the ruggedness of a chromatographic separation of a panel of synthetic cannabinoid drugs and metabolites following repeated injections of precipitated plasma.

Environmental Application and Method Compendium
Library Number: APNT134787739 | Format: PDF | File Size: 27912.12 kB | Year: 2014 | Content Type: Application Notes

This application notebook encompasses details about Environmental sample analysis and methods used.

Analysis of Urinary Catecholamines and Metanephrines Using Mixed-Mode SPE and Hydrophilic Interactio...
Library Number: APNT134805073 | Format: PDF | File Size: 1478.83 kB | Year: 2014 | Content Type: Application Notes

This application note describes the extraction and analysis of monoamine neurotransmitters and metanephrines from urine.

Multiresidue LC-MS/MS Screening of Veterinary Drugs in Milk Using the Ostro Sample Preparation Plate
Library Number: APNT134805080 | Format: PDF | File Size: 1866.27 kB | Year: 2014 | Content Type: Application Notes

This application note describes the use of the Ostro Plate for multi-residue screening for veterinary drugs in milk.

Advancing Host Cell Protein Analyses through the Combined Use of Microscale 2D RP/RP with CSH C18 an...
Library Number: APNT134800694 | Format: PDF | File Size: 2703.89 kB | Year: 2014 | Content Type: Application Notes

Here, recent advances in microscale peptide chromatography are applied to HCP analysis.

Development of a High Sensitivity SPE-LC-MS/MS Assay for the Quantification of Glucagon in Human Pla...
Library Number: APNT134803552 | Format: PDF | File Size: 2996.24 kB | Year: 2014 | Content Type: Application Notes

The combination of ionKey/MS, mixed-mode μElution SPE, and higher m/z b or y ion MS fragments provided the level of selectivity and sensitivity necessary to accurately quantify low pg/mL concentrations of glucagon in extracted plasma.

Determination and Characterization of Perfluoroalkyl and Polyfluoroalkyl Substances (PFAS’s) in Envi...
Library Number: APNT134803616 | Format: PDF | File Size: 2727.97 kB | Year: 2014 | Content Type: Application Notes

In this application note we explore the use of the ACQUITY UPLC I-Class System combined with ion mobility as an important tool for the unequivocal identification of PFOS isomers in environmental samples.

Analysis of Flavonoids in Juices with the ACQUITY QDa Detector
Library Number: APNT134803629 | Format: PDF | File Size: 1486.54 kB | Year: 2014 | Content Type: Application Notes

This application note describes a fast, simple, and reliable method for the QC and profiling of flavonoids in citrus species using the ACQUITY UPLC H-Class System and the ACQUITY QDa Detector.

Rapid Quantitative Analysis of 12 Mycotoxins in Processed Maize Using Myco6in1+ Immunoaffinity Clean...
Library Number: APNT134803632 | Format: PDF | File Size: 1363.25 kB | Year: 2014 | Content Type: Application Notes

In this application note, we describe a simple and accurate method for the quantitative analysis of multiple mycotoxins in processed maize using an immuno-affinity cleanup method and a single detector.

Direct Analysis of Opioids and Metabolites in Oral Fluid by Mixed-mode μElution SPE Combined with UP...
Library Number: APNT134775979 | Format: PDF | File Size: 1346.63 kB | Year: 2014 | Content Type: Application Notes

This application highlights a method for the analysis of 26 opioid drugs and metabolites by mixed-mode SPE followed by UPLC®-MS/MS. Glucuronide metabolites are directly analyzed, eliminating the need for enzymatic or chemical hydrolysis.

Using UPLC-MS/MS for Workplace Drug Testing
Library Number: APNT134803384 | Format: PDF | File Size: 652.54 kB | Year: 2014 | Content Type: Application Notes

The aim of this technology brief is to develop a UPLC®-MS/MS method for the analysis of 21 substances, commonly measured in workplace drug testing (WPDT) schemes, using a simple dilution of the urine prior to analysis.

Discovery of Pesticide Protomers Using Routine Ion Mobility Screening
Library Number: APNT134803216 | Format: PDF | File Size: 2396.85 kB | Year: 2014 | Content Type: Application Notes

In this application note, we explore the use of ion mobility with high resolution mass spectrometry as an important tool to gain a greater understanding of ion ratio variations. This technique offers some unique advantages to profiling complex matrices.

Collision Cross Section: A New Identification Point for a “Catch All” Non-Targeted Screening Approac...
Library Number: APNT134803219 | Format: PDF | File Size: 3559.69 kB | Year: 2014 | Content Type: Application Notes

In this application note, we present Collision cross section (CCS), derived from ion mobility drift times, as a new identification parameter that can efficiently reduce the number of false detections when used in combination with conventional accurate mas...

Use of Ion Mobility Spectral Cleanup and Collision Cross Section Values to Increase Confidence and E...
Library Number: APNT134803238 | Format: PDF | File Size: 2310.44 kB | Year: 2014 | Content Type: Application Notes

In this application note, we explore the feasibility of using the ACQUITY UPLC I-Class System in combination with ion mobility mass spectrometry (IMS-MS) as a new strategic approach for the screening of pesticide residues in food.

Utility of the ACQUITY UPLC I-Class System and Ion Mobility in a Routine Workflow to Understand the ...
Library Number: APNT134803225 | Format: PDF | File Size: 2895.54 kB | Year: 2014 | Content Type: Application Notes

This application note explores the use of routine screening with UPLC and ion mobility to identify multiple protonation sites and different fragmentation patterns within the fluoroquinolone class of antibiotics.

Determination of Brominated Vegetable Oil in Soft Drinks by UPC2/MS
Library Number: APNT134802704 | Format: PDF | File Size: 1550.6 kB | Year: 2014 | Content Type: Application Notes

This application note demonstrates a rapid and simple analysis of BVO in soft drinks and beverages using Convergence Chromatography and tandem mass spectrometry.