Literature


Description
Evaluation of the Potential of the ACQUITY QDa Mass Detector for Use in Forensic Chemistry and Drug ...
Library Number: APNT134938514 | Format: PDF | File Size: 632.46 kB | Year: 2017 | Content Type: Application Notes

This technology brief assess the transferability of an existing toxicology library to the Acquity QDa mass detector.

UPLC and APGC Multi Residue Pesticide Analysis on a Single Tandem Quadrupole Mass Spectrometer Platf...
Library Number: APNT134938251 | Format: PDF | File Size: 2916.37 kB | Year: 2017 | Content Type: Application Notes

In this application note, a single GC-MS-MS and LC-MS-MS workflow for the multi residue analysis of pesticides is demonstrated on a variety of fruit and vegetable samples.

Targeted and Untargeted Screening of Microcystins in Lake Water Samples Using High Resolution Mass S...
Library Number: APNT134938229 | Format: PDF | File Size: 1858.79 kB | Year: 2017 | Content Type: Application Notes

In this application note, we describe a method that combines UPLC and HRMS to perform targeted screening of microcystins. Using a data-independent approach, additional compounds that were not included at the time of the initial analysis could be investig...

Real-Time Analysis of Flavors Using DART and the ACQUITY QDa Mass Detector
Library Number: APNT134938089 | Format: PDF | File Size: 1021.15 kB | Year: 2017 | Content Type: Application Notes

This application note demonstrates the utility of DART (direct analysis in real time) and ACQUITY QDa mass detection for rapid, accurate, and cost-effective flavor characterization, for monitoring product quality, and reducing production costs

Sensitive and Reproducible LC-MS Quantification of C-Reactive Protein in Plasma: A Potential Biomark...
Library Number: APNT134916496 | Format: PDF | File Size: 837.11 kB | Year: 2016 | Content Type: Application Notes

This application note describes a generic, kit based approach for protein quantification.

Separation of Low Levels of Isoleucine from Leucine Using the ACQUITY UPLC H-Class Amino Acid System
Library Number: APNT | Format: PDF | File Size: 1564.01 kB | Year: 2015 | Content Type: Application Notes

Resolution of leucine and isoleucine at levels as low as 0.05% Ile/Leu using the UPLC Amino Acid Analysis Solution.

Selecting a Reversed-Phase Column for the Peptide Mapping Analysis of a Biotherapeutic Protein
Library Number: APNT134935546 | Format: PDF | File Size: 1306.48 kB | Year: 2017 | Content Type: Application Notes

This application note focuses on reversed-phase (RP) column selection considerations for peptide mapping.

Advantages of Oasis PRiME HLB for the LC-MS/MS Analysis of Vitamin D Metabolites in Serum for Clinic...
Library Number: APNT134937156 | Format: PDF | File Size: 713.22 kB | Year: 2017 | Content Type: Application Notes

This technology brief describes a LC-MS/MS method for the analysis of Vitamin D metabolites.

Oasis PRiME HLB Food Applications Notebook
Library Number: APNT134935885 | Format: PDF | File Size: 4063.04 kB | Year: 2017 | Content Type: Application Notes

In this booklet learn how Oasis PRiME HLB cleans up challenging food samples.

Structural Elucidation of an Unknown Compound in the Fatty Acid Methyl Esters (FAMEs) Extract of Avo...
Library Number: APNT134937004 | Format: PDF | File Size: 1416.82 kB | Year: 2017 | Content Type: Application Notes

Employing high resolution mass spectrometry (HRMS) and atmospheric pressure chemical ionization following gas chromatography (APGC), the accurate mass of the molecular ion and generated fragments were used to propose an identification of the unknown compo...

Oasis PRiME HLB Cartridges Now Available in Syringe Compatible Plus Format
Library Number: APNT134936788 | Format: PDF | File Size: 884.47 kB | Year: 2017 | Content Type: Application Notes

This technology brief demonstrates Oasis® PRiME HLB Cartridges in formats suitable for processing samples with or without the need for a vacuum/positive pressure manifold.

Analysis of Corticosteroids and Androgens in Serum for Clinical Research
Library Number: APNT134936586 | Format: PDF | File Size: 631.45 kB | Year: 2017 | Content Type: Application Notes

This application note describes a clinical research method for the analysis of steroid hormones in Plasma.

Analysis of Serum Cortisol, Androstenedione, and 17-hydroxyprogesterone Using 2D UPLC-MS/MS for Clin...
Library Number: APNT134936592 | Format: PDF | File Size: 505.59 kB | Year: 2017 | Content Type: Application Notes

This technology brief describes a 2D UPLC-MS/MS method for the quantitative measurement of steroid hormones.

Advantages of CORTECS UPLC T3 Columns for the Detection of Coenzyme Q10 in Plasma for Clinical Resea...
Library Number: APNT134936424 | Format: PDF | File Size: 463.01 kB | Year: 2017 | Content Type: Application Notes

The analysis of Coenzyme Q10 in plasma is described in this technology brief.

Factors Influencing Diastereomer Separations in Oligonucleotide Analysis
Library Number: APNT134936429 | Format: PDF | File Size: 365.12 kB | Year: 2017 | Content Type: Application Notes

This technology brief demonstrates the separation of diastereomers containing oligonucleotide samples.

The Impact of Adducts and Strategies to Control Them in IP-RPLC Based Oligonucleotide Analyses
Library Number: APNT134936452 | Format: PDF | File Size: 569.88 kB | Year: 2017 | Content Type: Application Notes

This technology brief describes IP-RPLC based analyses of oligonucleotides.

Ovarian Cancerous Tissue Identification by DESI Imaging for Clinical Research
Library Number: APNT134936067 | Format: PDF | File Size: 1904.28 kB | Year: 2017 | Content Type: Application Notes

Identification and characterization of ovarian cancer tissue samples by DESI imaging for clinical research studies.

Examples of USP Method Modernizations Using “Equivalent L/dp” and “Equivalent N” Allowed Changes wit...
Library Number: APNT134935710 | Format: PDF | File Size: 762.14 kB | Year: 2017 | Content Type: Application Notes

This technology brief demonstrates development of faster methods with lower solvent consumption using CORTECS columns in USP method modernizations.

SFC Analytical to Preparative Scale Up of Similar Compounds with Torus DIOL 1.7 μm and 5 μm Columns:...
Library Number: APNT134935721 | Format: PDF | File Size: 527.6 kB | Year: 2017 | Content Type: Application Notes

This technology brief demonstrates the analytical to preparative scale up of an SFC separation using matched average column pressure (ACP) with Torus™ Columns.

LC-MS/MS Analysis of Urinary Benzodiazepines and Z-drugs via a Simplified, Mixed-Mode Sample Prepara...
Library Number: APNT134935741 | Format: PDF | File Size: 463.29 kB | Year: 2017 | Content Type: Application Notes

This application note describes a rapid and simplified solid phase extraction protocol and LC-MS/MS method for the analysis of urinary benzodiazepines and metabolites.

Solid Phase Extraction and Analysis of Coenzyme Q10 from Plasma Using Oasis PRiME HLB for Clinical R...
Library Number: APNT134935748 | Format: PDF | File Size: 323.48 kB | Year: 2017 | Content Type: Application Notes

This application note details the efficient extraction and analysis of CoQ10 from plasma samples.

Analysis of Busulfan in Plasma for Clinical Research
Library Number: APNT134935759 | Format: PDF | File Size: 851.87 kB | Year: 2017 | Content Type: Application Notes

In this application note analysis of plasma busulfan has been developed by an analytically sensitive and selective clinical research method.

Oasis PRiME HLB Cartridges for Rapid and Effective Removal of Chlorophyll from QuEChERS Spinach Extr...
Library Number: APNT134935361 | Format: PDF | File Size: 734.34 kB | Year: 2017 | Content Type: Application Notes

This technology brief demonstrates Oasis PRiME HLB Sorbent in both Vac and Plus Formats.

Integrating Cost-Effective Mass Detection into Oligonucleotide Analyses with the ACQUITY QDa
Library Number: APNT134934824 | Format: PDF | File Size: 510.71 kB | Year: 2017 | Content Type: Application Notes

This technology brief demonstrates that the ACQUITY QDa Detector is able to detect and report mass information for a diverse set of oligonucleotides.

Rapid, Simple, and Effective Clean-up of Bovine Liver Samples Prior to UPLC-MS/MS Multiresidue Veter...
Library Number: APNT134929312 | Format: PDF | File Size: 728.94 kB | Year: 2017 | Content Type: Application Notes

This application note determines the range of veterinary drug residues in tissue samples with a single analytical method.