Literature


Description
ACQUITY QDa Detector QC Applications Compendium
Library Number: APNT134920530 | Format: PDF | File Size: 12125.72 kB | Year: 2017 | Content Type: Application Notes

Here we learn the application of QDa detector in QC workflow improvement.

Strategies for On-Line Sample Enrichment and Confirmation of Analytes in a Complex Food Matrix
Library Number: APNT134921200 | Format: PDF | File Size: 414.99 kB | Year: 2017 | Content Type: Application Notes

In this application note, learn how mass detection can be deployed in food QC lab environments to provide the selectivity and sensitivity necessary to detect low levels of compounds in complex matrices, such as orange juice.

Rapid Screening of Skin Lightening Products for the Corticosteroid Clobetasol Propionate Using Direc...
Library Number: APNT134921103 | Format: PDF | File Size: 477.46 kB | Year: 2017 | Content Type: Application Notes

A powerful detection method for the rapid qualitative determination of active ingredients (AIs) and other ingredients in cosmetics samples using a direct ionization technique with mass detection.

Oligonucleotides Applications Notebook
Library Number: APNT10094756 | Format: PDF | File Size: 7686.18 kB | Year: 2008 | Content Type: Application Notes

This compilation includes an overview of Waters UPLC and MS technologies, along with Oligonucleotide Separation Technology (OST) columns, for oligonucleotide analysis, as well as supportive application work.

Analysis of Testosterone Using the Xevo TQ-XS for Clinical Research
Library Number: APNT134919224 | Format: PDF | File Size: 512.07 kB | Year: 2016 | Content Type: Application Notes

The analysis of testosterone is carried out for clinical research studies.

Quantitative Determination of Urinary COOH-THC for Forensic Toxicology: Comparison to a Validated Re...
Library Number: APNT134919758 | Format: PDF | File Size: 221.63 kB | Year: 2016 | Content Type: Application Notes

This application note details an inter laboratory comparison of COOH-THC quantification using Oasis PRiME HLB.

APGC-MS/MS Investigation of a Complex Mixture of Polyhalogenated Dioxins and Furans (PXDD/Fs) Genera...
Library Number: APNT134919768 | Format: PDF | File Size: 406.13 kB | Year: 2016 | Content Type: Application Notes

Learn how APGC coupled to a Xevo TQ-S tandem quadrupole instrument can better characterize dioxin and furan generation (polybromo- and mixed halogenated) that firefighters and first responders are exposed to.

The Direct Quantification of a Mutagenic Impurity, Methyl Amino Crotonate, Using ACQUITY UPC2 and QD...
Library Number: APNT134919219 | Format: PDF | File Size: 333.42 kB | Year: 2016 | Content Type: Application Notes

The analysis of MAC (Methyl-3-aminocrotonate) is studied in this application note.

Fast Analysis of Isoflavones in Dietary Supplements – USP Method Transfer onto a UHPLC System
Library Number: APNT134919286 | Format: PDF | File Size: 324.67 kB | Year: 2016 | Content Type: Application Notes

This application note demonstrates the transfer of the USP method onto an ACQUITY Arc UHPLC System and the AQUITY QDa Mass Detector with reduced analysis time of isoflavones from 74 min to 18 min.

Determination of the Metabolites of Nitrofuran Antibiotics in Animal Tissues and Food Products by UP...
Library Number: APNT134919289 | Format: PDF | File Size: 436.82 kB | Year: 2016 | Content Type: Application Notes

In this application note, we describe a Specific, targeted UPLC-MS/MS method for nitrofurans determination in a range of sample types that meet requirements for both official control and food business operators’ pre-export testing.

Fast Analysis of Isoflavones in Dietary Supplements – Benefits of Mass Detection in Method Transfer ...
Library Number: APNT134919282 | Format: PDF | File Size: 732.19 kB | Year: 2016 | Content Type: Application Notes

This application note demonstrates the benefits of the ACQUITY QDa Detector for the analysis of isoflavones in dietary supplements, including Reduced method development and transfer times, improved data quality and simplified peak detection.

DMB-Labeled Sialic Acid Analyses Using HPLC-, UHPLC-, and UPLC-Based, BEH C18 Columns
Library Number: APNT134870781 | Format: PDF | File Size: 759.89 kB | Year: 2016 | Content Type: Application Notes

This application extends on Waters technologies for the analysis of intact glycoproteins, glycoprotein subunits, glycopeptides, as well as released N-Linked glycans from biotherapeutic glycoproteins and related compounds.

Detection of Cocaine and Its Major Metabolites in Rodent Bone Following Outdoor Decomposition after ...
Library Number: APNT134919105 | Format: PDF | File Size: 1392.88 kB | Year: 2016 | Content Type: Application Notes

Analysis of cocaine and its metabolites is studied in this application note.

Optimizing HILIC-based Analyses of RapiFluor-MS Labeled Sialylated N-Glycans
Library Number: APNT134918682 | Format: PDF | File Size: 927.6 kB | Year: 2016 | Content Type: Application Notes

This application note describes applied hydrophilic interaction chromatography for the analysis of RapiFluor-MS labeled sialylated N-glycans.

High Definition Imaging (HDI) 1.4: Lock Mass Recalibration for MS Imaging Data Sets
Library Number: APNT134918626 | Format: PDF | File Size: 1293.23 kB | Year: 2016 | Content Type: Application Notes

This technology brief gives an overview on external and internal calibration for improved mass accuracy in MS imaging data sets.

ProMass for MassLynx Software for Oligonucleotide Analysis
Library Number: APNT10174847 | Format: PDF | File Size: 2601.06 kB | Year: 2010 | Content Type: Application Notes

ProMass for MassLynx Software enables batch mass deconvolution and data analysis for UPLC/MS data generated on both single quadrupole and time-of-flight Waters MS instruments. ProMass for MassLynx is the only software available on the market that performs...

UPLC-MS/MS Method for the Routine Analysis of Tobacco Specific Nitrosamines (TSNAs) in Tobacco Produ...
Library Number: APNT134918320 | Format: PDF | File Size: 225.53 kB | Year: 2016 | Content Type: Application Notes

In this technology brief, we describe an optimized UPLC-MS/MS method for TSNA analysis in tobacco products that has been developed using RADAR Technology.

Hexylammonium Acetate as an Ion-Pairing Agent for IP-RP LC Analysis of Oligonucleotides
Library Number: APNT10152270 | Format: PDF | File Size: 2122.81 kB | Year: 2010 | Content Type: Application Notes

In this application note we describe the preparation of hexylammonium acetate (HAA) and the benefits to its use for a variety of applications compared to TEAA and/or TEA-HFIP for the analysis of oligonucleotides.

Stability of the ACQUITY UPLC System with Xevo G2-XS QTof Mass Spectrometer for Metabolic Phenotypin...
Library Number: APNT134918033 | Format: PDF | File Size: 634.17 kB | Year: 2016 | Content Type: Application Notes

This technology brief evaluates the suitability of the Waters ACQUITY UPLC System with Xevo G2-XS QTof MS for the analysis of biological fluids.

UPLC Analysis of Phosphorothioate Oligonucleotides: Method Development
Library Number: APNT10014831 | Format: PDF | File Size: 1292.52 kB | Year: 2008 | Content Type: Application Notes

In this application note, we illustrate and provide guidelines for fast, high resolution, and efficient analysis of therapeutic phosphorothioate oligonucleotides in a single analysis method.

Developing a Novel, Integrated LC-MS Workflow for High-resolution Monitoring and Characterization of...
Library Number: APNT134917954 | Format: PDF | File Size: 1820.46 kB | Year: 2016 | Content Type: Application Notes

This application note describes an integrated LC-MS workflow for identification, impurity profiling, and MS/MS characterization of oligonucleotides using high-resolution mass spectrometry.

Modernization of a HILIC USP Impurity Method for Cetirizine Hydrochloride Tablets
Library Number: APNT134917789 | Format: PDF | File Size: 237.6 kB | Year: 2016 | Content Type: Application Notes

This technology brief describes the USP method for the analysis of organic impurities in cetirizine hydrochloride

Evaluation of Alternative Ion-pairing Reagents in the Analysis of Oligonucleotides with the ACQUITY ...
Library Number: APNT134917652 | Format: PDF | File Size: 776.84 kB | Year: 2016 | Content Type: Application Notes

This application note evaluates the applicability of alternative IP reagents in the analysis of oligonucleotides.

Peptide and Protein Bioanalysis Application Notebook
Library Number: APNT134830620 | Format: PDF | File Size: 19661.64 kB | Year: 2017 | Content Type: Application Notes

This application notebook details on peptide & protein bioanalysis.

Quantitative Analysis of THC and its Metabolites in Plasma Using Oasis PRiME HLB for Toxicology and ...
Library Number: APNT134916779 | Format: PDF | File Size: 334.06 kB | Year: 2016 | Content Type: Application Notes

This application note details the extraction of THC and metabolites from plasma samples using a novel SPE sorbent for forensic toxicology applications.