Literature


Description
Multi-Residue Pesticide Analysis in Tea: Optimized Cleanup After QuEChERS Extraction for UPLC-MS/MS ...
Library Number: APNT134775094 | Format: PDF | File Size: 1711.88 kB | Year: 2015 | Content Type: Application Notes

This application note presents QuEChERS extraction and SPE-based cleanup strategies for multi-residue pesticide analysis of dried teas.

Characterization of Biotherapeutics: ACQUITY UPLC H-Class Bio with 2D Part 1 of 3: On-line Desalting...
Library Number: APNT134836823 | Format: PDF | File Size: 2446.9 kB | Year: 2015 | Content Type: Application Notes

In this application note we demonstrate the characterization of biotherapeutics with the ACQUITY UPLC H-Class Bio System with 2D Technology.

Characterization of Biotherapeutics: ACQUITY UPLC H-Class Bio with 2D Part 2 of 3: Rendering a Viabl...
Library Number: APNT134836856 | Format: PDF | File Size: 2723.36 kB | Year: 2015 | Content Type: Application Notes

This application note demonstrates that the ACQUITY UPLC H-Class Bio System with 2D Technology is a viable option for interfacing IEX to electrospray ionization (ESI)-MS.

Characterization of Biotherapeutics: ACQUITY UPLC H-Class Bio with 2D Part 3 of 3: On-line Enrichmen...
Library Number: APNT134836863 | Format: PDF | File Size: 2845.94 kB | Year: 2015 | Content Type: Application Notes

The objective of this application note is to demonstrate that the ACQUITY UPLC H-Class Bio System with 2D Technology is suited for fractionation and enrichment of low abundant species in biological samples.

Non-Targeted Screening Analysis of Packaging Extracts Using the UNIFI Scientific Information System
Library Number: APNT134836651 | Format: PDF | File Size: 2207.96 kB | Year: 2015 | Content Type: Application Notes

This application note describes an LC-MS and Informatics workflow, which employs high-resolution mass spectrometry, that can be adopted for cosmetics, food, and pharmaceutical packaging extractable applications.

Exploiting RapiFluor-MS Labeling to Monitor Diverse N-Glycan Structures via Fluorescence and Mass De...
Library Number: APNT134836333 | Format: PDF | File Size: 1395.8 kB | Year: 2015 | Content Type: Application Notes

In this application note we present the utility of RapiFluor-MS coupled with UPLC®-FLR-MS for monitoring labeled glycans ranging across a range of properties, masses, and relative abundance.

Benefits of Using Mass Detection for Assessing Quality and Purity of Cetrimonium Bromide Pharmaceuti...
Library Number: APNT134836200 | Format: PDF | File Size: 1713.63 kB | Year: 2015 | Content Type: Application Notes

In this application note, we present a robust and quick UPLC method for analysis of cetrimonium bromide raw material.

Targeted Lipidomics of Oxylipins (Oxygenated Fatty Acids)
Library Number: APNT134732486 | Format: PDF | File Size: 2178.83 kB | Year: 2015 | Content Type: Application Notes

An SPE UPLC/MRM MS assay is presented for the routine high-throughput detection of more than 100 oxylipins and free fatty acids in plasma.

Routine MS Detection for USP Chromatographic Methods
Library Number: APNT134834272 | Format: PDF | File Size: 2039.87 kB | Year: 2015 | Content Type: Application Notes

This application note presents a systematic protocol for using MS detection directly with unmodified USP methods. The USP assay for Irbesartan is used as an example to illustrate the peak transfer protocol.

Multiple, Sequential DESI Images from a Single Tissue Section at Different Spatial Resolution
Library Number: APNT134833822 | Format: PDF | File Size: 1537.84 kB | Year: 2015 | Content Type: Application Notes

This technology brief demonstrates that desorption electrospray ionization (DESI) imaging can be utilized as a non-destructive imaging technique, which allows multiple analyses in rapid succession on the same tissue section at different spatial resolution...

Metabolic Phenotyping Using Atmospheric Pressure Gas Chromatography-MS
Library Number: APNT134832772 | Format: PDF | File Size: 3853.34 kB | Year: 2015 | Content Type: Application Notes

This application note reports an APGC-TOF MSE profiling approach and its application to metabolic fingerprinting of Arabidopsis.

Pesticide Screening of Food Samples Using the ionKey/MS System
Library Number: APNT134787026 | Format: PDF | File Size: 1598.28 kB | Year: 2015 | Content Type: Application Notes

In this application note, The ionKey/MS System, a novel microfluidics-MS platform, was assessed for the micro-LC analysis of pesticides in food samples.

Enantioseparation of Metalaxyl Using ACQUITY UPC2 and Small-Scale Purification Using the Investigato...
Library Number: APNT134832282 | Format: PDF | File Size: 1723.39 kB | Year: 2015 | Content Type: Application Notes

In this application note, we present the chiral resolution of metalaxyl using the ACQUITY UPC2 System, followed by scaling to a semi-preparative purification using the Investigator SFC System.

Characterization of Impurities in the Fungicide Flutriafol Using UNIFI
and UPLC-ToF-MS(E)

Library Number: APNT134832285 | Format: PDF | File Size: 2681.73 kB | Year: 2015 | Content Type: Application Notes

In this application note, the ACQUITY UPLC I-Class System coupled to the Xevo G2-XS QTof and PDA Detector were used to analyze technical-grade flutriafol material.

Generation of Multiple Images from a Single Tissue Section with Dual Polarity Desorption Electrospra...
Library Number: APNT134831781 | Format: PDF | File Size: 2246.84 kB | Year: 2015 | Content Type: Application Notes

This technology brief demonstrates the flexibility of desorption electrospray ionization (DESI) imaging, showing that the same tissue can repeatedly be imaged at the molecular level in positive and negative ion mode, to maximize information about molecula...

Determination of Triphenylmethane Dyes and Their Metabolites in Shrimp Using QuEChERS Extraction and...
Library Number: APNT134831846 | Format: PDF | File Size: 1405.19 kB | Year: 2015 | Content Type: Application Notes

In this application note, we report a highly sensitive and efficient LC-MS/MS method for simultaneously analyzing triphenylmethane (TPM) dyes in shrimp.

Transfer of an Isocratic USP Assay from an Agilent 1100 Series LC System to a ACQUITY UPLC H-Class S...
Library Number: APNT134830915 | Format: PDF | File Size: 1812.79 kB | Year: 2015 | Content Type: Application Notes

In this technology brief an HPLC USP method transfer from an Agilent 1100 Series LC System to an ACQUITY UPLC® H-Class System was demostrated meeting all USP method criteria.

Utility of Desorption Electrospray Ionization (DESI) for Mass Spectrometry Imaging
Library Number: APNT134830937 | Format: PDF | File Size: 1654.08 kB | Year: 2015 | Content Type: Application Notes

This technology brief describes the DESI imaging technique as applied to mass spectrometry imaging using time-of-flight (TOF) mass spectrometers, such as the SYNAPT® G2-Si or the Xevo® G2-XS.

Benefits of Using Mass Detection for Pharmaceutical Raw Materials Analysis of 1-(3-Dimethylaminoprop...
Library Number: APNT134830752 | Format: PDF | File Size: 1797.04 kB | Year: 2015 | Content Type: Application Notes

Here we describe a robust and quick UPLC method for analysis of EDC HCl.

Peptide and Protein Bioanalysis Application Notebook
Library Number: APNT134830620 | Format: PDF | File Size: 19661.64 kB | Year: 2015 | Content Type: Application Notes

This application notebook details on peptide & protein bioanalysis.

Purification of Cannabidiol from Hemp Oil Using the Prep150 LC System
Library Number: APNT134830443 | Format: PDF | File Size: 1844.3 kB | Year: 2015 | Content Type: Application Notes

This application note will describe the purification of Cannabidiol CBD from a CBD-rich paste using the Waters® Prep 150 LC System.

LC-MS/MS Analysis of Pesticide Residues in Rice and Unexpected Detection of Residues in an Organic R...
Library Number: APNT134830407 | Format: PDF | File Size: 1894.98 kB | Year: 2015 | Content Type: Application Notes

In this application note, we describe a rapid, multi-residue method for the determination of over 200 pesticides in basmati rice using a simple QuEChERS sample preparation procedure followed by UPLC-MS-MS.

High Sensitivity Analysis of Opioids in Oral Fluid Using ionKey/MS
Library Number: APNT134830068 | Format: PDF | File Size: 1011.02 kB | Year: 2015 | Content Type: Application Notes

This technology brief demonstrates the separation and high sensitivity detection of opioids in oral fluid using the ionKey/MS System.

Future Proofing the Biopharmaceutical QC Laboratory: Chromatographic Scaling of HPLC Monosaccharide ...
Library Number: APNT134829823 | Format: PDF | File Size: 1552.35 kB | Year: 2015 | Content Type: Application Notes

In this application note in the series "Furture Proofing the Biopharmaceutical QC Laboratory", we illustrate the transfer of a robust HPLC monosaccharide method to the ACQUITY UPLC H-Class Bio System running as an HPLC, using monosaccharide standards as w...

Separation of Low Levels of Isoleucine from Leucine Using the ACQUITY UPLC H-Class Amino Acid System
Library Number: APNT | Format: PDF | File Size: 1564.01 kB | Year: 2015 | Content Type: Application Notes

Resolution of leucine and isoleucine at levels as low as 0.05% Ile/Leu using the UPLC Amino Acid Analysis Solution.