Literature


Description
Simple and Effective Clean-up for UPLC-MS/MS Determination of Veterinary Drug Residues in Egg
Library Number: APNT134905944 | Format: PDF | File Size: 725.51 kB | Year: 2016 | Content Type: Application Notes

This application note determines wide variety of veterinary drugs in eggs.

Reducing Sample Volume and Increasing Sensitivity for the Quantification of Human Insulin and 5 Anal...
Library Number: APNT134809163 | Format: PDF | File Size: 2501.06 kB | Year: 2016 | Content Type: Application Notes

In this application structures for human insulin and their analogs were quantified.

A Scaled USP Method for Fluconazole Using an ACQUITY UPLC
Library Number: APNT134905173 | Format: PDF | File Size: 385.6 kB | Year: 2016 | Content Type: Application Notes

This application note desbribes how we can increase throughput by scaling methods from HPLC to UPLC.

REIMS Workflow for the Direct Analysis of Cell Pellets with Minimal Sample Preparation
Library Number: APNT134905228 | Format: PDF | File Size: 1382.36 kB | Year: 2016 | Content Type: Application Notes

A powerful method of analyzing cell samples with minimal sample preparation is described in this technology brief.

Improved Performance and Cycle Time for the Analysis of Lipid Soluble Antioxidants Using CORTECS T3 ...
Library Number: APNT134904359 | Format: PDF | File Size: 245.56 kB | Year: 2016 | Content Type: Application Notes

This application note describes HPLC method transfer to UHPLC for the analysis of lipid soluble antioxidants.

A Rapid, Kit-based Approach for LC-MS/MS Quantification of Apolipoprotein A1 in Plasma
Library Number: APNT134904184 | Format: PDF | File Size: 363.13 kB | Year: 2016 | Content Type: Application Notes

This application describes a fast and standardized kit-based approach that is capable of quantifying Apolipoprotein A1 accurately and reproducibly in plasma.

ACQUITY Advanced Polymer Chromatography (APC) Columns Applications Notebook
Library Number: APNT134739527 | Format: PDF | File Size: 1809.28 kB | Year: 2016 | Content Type: Application Notes

This applications notebook contains application notes featuring ACQUITY Advanced Polymer Chromatography (APC) Columns and System authored by Waters scientists.

Exploiting the Orthogonality of the ACQUITY UPC2 System to Develop an Impurities Method for Ondanset...
Library Number: APNT134903247 | Format: PDF | File Size: 254.84 kB | Year: 2016 | Content Type: Application Notes

This application note describes retention of small polar compounds using UPC2 and simplified method development using ACQUITY QDa.

Fatty Acid Profiling by UPC2-MS
Library Number: APNT134902890 | Format: PDF | File Size: 926.98 kB | Year: 2016 | Content Type: Application Notes

In this technology brief, we describe a fast and simple approach for the profiling of fatty acids in food.

Biopharmaceutical Platform Solution with UNIFI - Key Applications
Library Number: APNT134778433 | Format: PDF | File Size: 26474.86 kB | Year: 2016 | Content Type: Application Notes

The Biopharmaceutical Platform Solution with UNIFI® enables laboratories to efficiently acquire, process, and communicate information from high resolution analytical studies.

High Definition Imaging Software: New “Data Processing” Functionality
Library Number: APNT134901932 | Format: PDF | File Size: 767.47 kB | Year: 2016 | Content Type: Application Notes

This technology brief demonstrates the newly integrated data-processing capability of Waters® High Definition Imaging Software (HDI®).

Quantitative Analysis of THC and its Metabolites in Whole Blood Using LC-MS/MS for Toxicology and Fo...
Library Number: APNT134901925 | Format: PDF | File Size: 313.84 kB | Year: 2016 | Content Type: Application Notes

This application note details the extraction of THC and its metabolites from whole blood samples using a novel SPE sorbent, Oasis PRiME HLB, in a μElution format for forensic toxicology applications.

Profiling Mono and Disaccharides in Milk and Infant Formula Using the ACQUITY Arc System and ACQUITY...
Library Number: APNT134900891 | Format: PDF | File Size: 571.8 kB | Year: 2016 | Content Type: Application Notes

In this application note, learn how the combination of chromatographic retention time and mass information can provide improved selectivity for the profiling of sugars and sugar alcohols.

Application of High- and Low-resolution Mass Spectrometers Combined with Nanoscale LC and Microfluid...
Library Number: APNT134900402 | Format: PDF | File Size: 524.52 kB | Year: 2016 | Content Type: Application Notes

This application note presents the comprehensive comparison of both tandem quadrupole and time-of-flight mass spectrometers for the quantitative MRM-based analysis of peptide biomarkers.

Analysis of Nucleosides by UltraPerformance Convergence Chromatography (UPC2)
Library Number: APNT134855713 | Format: PDF | File Size: 801.63 kB | Year: 2015 | Content Type: Application Notes

This technology brief demonstrates the advantages of utilizing UltraPerformance Convergence Chromatography™ (UPC2®) to address the analysis of highly polar compounds.

Combining RapiFluor-MS and UNIFI Scientific Information System for a Total N-linked Glycan Solution ...
Library Number: APNT134899853 | Format: PDF | File Size: 1736.91 kB | Year: 2016 | Content Type: Application Notes

In this application note, we describe a streamlined N-linked glycan analysis solution for innovator vs. biosimilar comparisons.

Waters 2016 Food Testing Application Notes Booklet
Library Number: APNT134800757 | Format: PDF | File Size: 11822.48 kB | Year: 2016 | Content Type: Application Notes

Read our in-depth application notes to learn about the latest analytical methods for profiling fatty acids, sugars, cinnamon, extractables, veterinary drugs, and pesticides.

Oasis PRiME HLB Cartridge for Cleanup of Infant Formula Extracts Prior to UPLC-MS/MS Multiresidue Ve...
Library Number: APNT134898729 | Format: PDF | File Size: 187.94 kB | Year: 2016 | Content Type: Application Notes

In this application note a simple and effective extraction/protein precipitation procedure was applied to the analysis of infant formula.

CASE STUDY 3: Quantitative and Qualitative Analysis of Perfluoroalkyl Substances (PFASs) in Wildlife...
Library Number: APNT134898813 | Format: PDF | File Size: 1449.68 kB | Year: 2016 | Content Type: Application Notes

In this application note, we demonstrate low-level detection and comprehensive data review of fluorinated environmental contaminants in wildlife using HRMS technologies and an integrated scientific information system.

Highly Analytically Sensitive Analysis of Aldosterone in Plasma on the Xevo TQ-XS for Clinical Resea...
Library Number: APNT134897347 | Format: PDF | File Size: 1005.33 kB | Year: 2016 | Content Type: Application Notes

In this technology brief, the Xevo TQ-XS was used to significantly improve the analytical sensitivity and imprecision of a LC-MS/MS method for the analysis of aldosterone in plasma for clinical research.

Improved Extraction of THC and its Metabolites from Oral Fluid Using Oasis PRiME HLB Solid Phase Ext...
Library Number: APNT134897294 | Format: PDF | File Size: 250.68 kB | Year: 2015 | Content Type: Application Notes

This application note details the extraction and analysis of THC and its major metabolites from oral fluid samples using an Oasis PRiME HLB μElution Plate, followed by UPLC-MS/MS analysis.

Streamline Method Development with Empower 3 MS Peak Tracking
Library Number: APNT134897305 | Format: PDF | File Size: 746.93 kB | Year: 2016 | Content Type: Application Notes

This technology brief demonstrates the use of Empower 3 MS Peak Tracking in the tracking of peak elution during development of a UPLC method for metoclopramide HCl and related substances by mass detection.

Ultimate Resolution HPLC-Based Size Exclusion Chromatography for the Analysis of Small Proteins and ...
Library Number: APNT134841954 | Format: PDF | File Size: 1595.62 kB | Year: 2015 | Content Type: Application Notes

This application note will cover the performance characteristics of this column, designed for the separation of small proteins and peptides, with respect to UPLC method transfer, column-to-column reproducibility, and column stability.

Rapid Screening of Fatty Acids in Oil Supplements Using Ambient Ionization (DART) and Mass Detection
Library Number: APNT134897040 | Format: PDF | File Size: 1509.35 kB | Year: 2016 | Content Type: Application Notes

In this application note, we demonstrate the utility and ease-of-use of DART coupled to single quadrupole mass detection for the identification and rapid authentication of omega-3 and omega-6 polyunsaturated fatty acids in oil supplements.

Rapid Profiling and Authentication of Cinnamon Samples Using Ambient Ionization (DART) and Single Qu...
Library Number: APNT134897051 | Format: PDF | File Size: 1884 kB | Year: 2016 | Content Type: Application Notes

In this application note, we describe a novel approach that employs DART and the ACQUITY QDa Detector for the simple and rapid analysis of cinnamon samples to determine species origin.