Literature


Description
Solutions Guide for Biopharmaceuticals
Library Number: APNT134910847 | Format: PDF | File Size: 13061.24 kB | Year: 2016 | Content Type: Application Notes

Approach to the Characterization and Monitoring of Protein-based Pharmaceutical Products

Antioxidant Isolation Using the Prep 150 LC System
Library Number: APNT134910903 | Format: PDF | File Size: 884.99 kB | Year: 2016 | Content Type: Application Notes

This application note demonstrates the isolation and purification of chlorogenic acid from Aronia berries.

Separation of Small Intact Proteins on CORTECS UPLC C8 1.6 μm Columns
Library Number: APNT134910673 | Format: PDF | File Size: 716.58 kB | Year: 2016 | Content Type: Application Notes

This technology brief demonstrates narrower peak widths observed using of CORTECS® UPLC® C8 1.6 μm Columns solid-core technology on the separation efficiency of small intact proteins.

Quantifying Primary Aromatic Amines in Polyamide Kitchenware Using the ACQUITY UPLC I-Class System a...
Library Number: APNT134909760 | Format: PDF | File Size: 556.42 kB | Year: 2016 | Content Type: Application Notes

In this application note we describe a LC-MS/MS method for the analysis of 23 common PAAs in kitchenware after migration using the ACQUITY UPLC I-Class System coupled to a Xevo TQ-S micro Mass Spectrometer.

Transferring Methods for Monoclonal Antibody Analysis from an Agilent 1260 Infinity Quaternary LC Sy...
Library Number: APNT134908703 | Format: PDF | File Size: 498.84 kB | Year: 2016 | Content Type: Application Notes

This application note demonstrates method equivalency between an Agilent 1260 Infinity Quaternary LC System and an ACQUITY Arc System for transfer of isocratic and gradient methods for monoclonal antibody analysis.

Forced Degradation of Cannabidiol
Library Number: APNT134908696 | Format: PDF | File Size: 736.71 kB | Year: 2016 | Content Type: Application Notes

The Use of Orthogonal Methods to Monitor the Major Degradation Products of Cannabidiol (CBD)

A Validated Method for the Quantification of Amino Acids in Mammalian Urine
Library Number: APNT134820198 | Format: PDF | File Size: 1657.54 kB | Year: 2014 | Content Type: Application Notes

In this application note a robust, reliable method for the absolute quantification of twenty amino acids and the relative quantification of a further eighteen amino acids in human urine has been developed and evaluated.

Improved Efficiency of Proteomics Data Processing Using Symphony Data Pipeline Software
Library Number: APNT134907921 | Format: PDF | File Size: 585.44 kB | Year: 2016 | Content Type: Application Notes

Symphony Data Pipeline is a newly introduced software product which enables the automation of data processing functions in a sequence following a Masslynx acquisition.

Simultaneous Determination of Nicotine and Related Impurities in E-Liquids and E-Cigarettes Using UP...
Library Number: APNT134907726 | Format: PDF | File Size: 525.34 kB | Year: 2016 | Content Type: Application Notes

The combination of ACQUITY UPLC H-Class System with ACQUITY PDA and ACQUITY QDa detectors enables the simultaneous analysis of nicotine and 7 related impurities in e-liquid and e-cigarettes.

Improving the Analysis of Triazole Fungicides in Wheat Straw Samples using UniSpray Ionization with ...
Library Number: APNT134907752 | Format: PDF | File Size: 754.25 kB | Year: 2016 | Content Type: Application Notes

This technology brief, evaluates the potential of Waters UniSpray source coupled with the ACQUITY UPC2 System and Xevo TQ-XS Mass Spectrometer versus ESI to improve peak response, repeatability and signal-to-noise for the analysis of triazole fungicides. ...

Simple and Effective Clean-up for UPLC-MS/MS Determination of Veterinary Drug Residues in Egg
Library Number: APNT134905944 | Format: PDF | File Size: 725.51 kB | Year: 2016 | Content Type: Application Notes

This application note determines wide variety of veterinary drugs in eggs.

Reducing Sample Volume and Increasing Sensitivity for the Quantification of Human Insulin and 5 Anal...
Library Number: APNT134809163 | Format: PDF | File Size: 2501.06 kB | Year: 2016 | Content Type: Application Notes

In this application structures for human insulin and their analogs were quantified.

A Scaled USP Method for Fluconazole Using an ACQUITY UPLC
Library Number: APNT134905173 | Format: PDF | File Size: 385.6 kB | Year: 2016 | Content Type: Application Notes

This application note desbribes how we can increase throughput by scaling methods from HPLC to UPLC.

REIMS Workflow for the Direct Analysis of Cell Pellets with Minimal Sample Preparation
Library Number: APNT134905228 | Format: PDF | File Size: 1382.36 kB | Year: 2016 | Content Type: Application Notes

A powerful method of analyzing cell samples with minimal sample preparation is described in this technology brief.

Improved Performance and Cycle Time for the Analysis of Lipid Soluble Antioxidants Using CORTECS T3 ...
Library Number: APNT134904359 | Format: PDF | File Size: 245.56 kB | Year: 2016 | Content Type: Application Notes

This application note describes HPLC method transfer to UHPLC for the analysis of lipid soluble antioxidants.

A Rapid, Kit-based Approach for LC-MS/MS Quantification of Apolipoprotein A1 in Plasma
Library Number: APNT134904184 | Format: PDF | File Size: 363.13 kB | Year: 2016 | Content Type: Application Notes

This application describes a fast and standardized kit-based approach that is capable of quantifying Apolipoprotein A1 accurately and reproducibly in plasma.

ACQUITY Advanced Polymer Chromatography (APC) Columns Applications Notebook
Library Number: APNT134739527 | Format: PDF | File Size: 1809.28 kB | Year: 2016 | Content Type: Application Notes

This applications notebook contains application notes featuring ACQUITY Advanced Polymer Chromatography (APC) Columns and System authored by Waters scientists.

Exploiting the Orthogonality of the ACQUITY UPC2 System to Develop an Impurities Method for Ondanset...
Library Number: APNT134903247 | Format: PDF | File Size: 254.84 kB | Year: 2016 | Content Type: Application Notes

This application note describes retention of small polar compounds using UPC2 and simplified method development using ACQUITY QDa.

Fatty Acid Profiling by UPC2-MS
Library Number: APNT134902890 | Format: PDF | File Size: 926.98 kB | Year: 2016 | Content Type: Application Notes

In this technology brief, we describe a fast and simple approach for the profiling of fatty acids in food.

Biopharmaceutical Platform Solution with UNIFI - Key Applications
Library Number: APNT134778433 | Format: PDF | File Size: 26474.86 kB | Year: 2016 | Content Type: Application Notes

The Biopharmaceutical Platform Solution with UNIFI® enables laboratories to efficiently acquire, process, and communicate information from high resolution analytical studies.

Quantitative Analysis of THC and its Metabolites in Whole Blood Using LC-MS/MS for Toxicology and Fo...
Library Number: APNT134901925 | Format: PDF | File Size: 313.84 kB | Year: 2016 | Content Type: Application Notes

This application note details the extraction of THC and its metabolites from whole blood samples using a novel SPE sorbent, Oasis PRiME HLB, in a μElution format for forensic toxicology applications.

High Definition Imaging Software: New “Data Processing” Functionality
Library Number: APNT134901932 | Format: PDF | File Size: 767.47 kB | Year: 2016 | Content Type: Application Notes

This technology brief demonstrates the newly integrated data-processing capability of Waters® High Definition Imaging Software (HDI®).

Profiling Mono and Disaccharides in Milk and Infant Formula Using the ACQUITY Arc System and ACQUITY...
Library Number: APNT134900891 | Format: PDF | File Size: 571.8 kB | Year: 2016 | Content Type: Application Notes

In this application note, learn how the combination of chromatographic retention time and mass information can provide improved selectivity for the profiling of sugars and sugar alcohols.

Analysis of Nucleosides by UltraPerformance Convergence Chromatography (UPC2)
Library Number: APNT134855713 | Format: PDF | File Size: 801.63 kB | Year: 2015 | Content Type: Application Notes

This technology brief demonstrates the advantages of utilizing UltraPerformance Convergence Chromatography™ (UPC2®) to address the analysis of highly polar compounds.

Application of High- and Low-resolution Mass Spectrometers Combined with Nanoscale LC and Microfluid...
Library Number: APNT134900402 | Format: PDF | File Size: 524.52 kB | Year: 2016 | Content Type: Application Notes

This application note presents the comprehensive comparison of both tandem quadrupole and time-of-flight mass spectrometers for the quantitative MRM-based analysis of peptide biomarkers.