The application of photodiode array technology to absorbance detection combines the benefits of sensitivity and highly linear detection of chromatographic peaks. The collection of the absorbance spectra of eluted peaks provides an opportunity to detect co-elution as well as confirm the identity of eluted peaks based on library matching. The design of an absorbance detector for liquid chromatography requires a balancing of several factors:
Spectral resolution for photodiode array based detectors
This white paper will discuss the relationship between noise, linear dynamic range and optical resolution. It will also consider the implications of the number of diodes used in the diode array to capture the spectral data.