SONAR – Delivering MS/MS Data from a DIA Experiment

Library Number:
LITR134944704
Part Number:
720006033EN
Author(s):
Waters
Source:
Waters
Content Type:
Literature
Content Subtype:
White Papers

SONAR™ is the newest DIA mode from Waters and is complementary to MSE. The strength of SONAR is its increased selectivity, which translates to cleaner MS/MS data, allowing both discovery and quantification from a single injection using commonly accepted and established workflows.

SONAR delivers this increased selectivity with rapid scan rates to provide the following analytical benefits:

  • All the information required for quantification and identification in a single injection
  • Scan rates compatible with UPLC speeds for reliable quantitation
  • Library searches are more reliable due to cleaner MS/MS spectra
  • Laboratory workflows become more efficient as time consuming method development associated with MS/MS analysis is removed

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