Metabolite Identification: Working with Large Preclinical Multispecies Data Sets

Library Number:
APNT134959055
Part Number:
720006106EN
Author(s):
Mark Wrona, Sherri Naughton, Yun Alelyunas, Russell Mortishire-Smith, and Jayne Kirk
Source:
Waters
Content Type:
Application Notes
Content Subtype:
Application Notes
Related Products:
SYNAPT G2-S MS
 
 
 

This application note demonstrates detailed and thorough workflows for identification and characterization of complex multispecies data sets. Trends and pharmacokinetic profiles for multiple metabolites were evaluated, which enabled confirmation of human metabolites in preclinical species.

UNIFI provides a comprehensive solution for studying drug metabolism in detail. All workflows were capable of processing both MS and IMS data for routine screening and metabolite identification. Flexible future proof options are also available to access large molecule and quantitative HRMS workflows on a single platform.


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