Increasing Throughput for the Analysis of Human Insulin and Related Biotherapeutic Analogs using the ionKey/MS System

Library Number:
APNT134957868
Part Number:
720006105EN
Author(s):
Michael Donegan, James Murphy, and Erin Chambers
Source:
Waters
Content Type:
Application Notes
Content Subtype:
Technical Notes
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This study highlights the novel and highly efficient ionKey/MS System, combined with the robust and high throughput 300 μm I.D. iKey HT separation device for the highly sensitive and accurate quantification of therapeutic insulin and five analogs using tandem quadrupole LC-MS.

The fully integrated ionKey/MS System enables bioanalysts the flexibility to modulate a microflow LC-MS system between ultra sensitivity analysis and higher throughput by simply switching between the novel iKey columns.


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