Bioseparations Applications Notebook: Tools, Techniques, and Insights into Biopharmaceutical Analysis

Library Number:
APNT134922566
Part Number:
720005536EN
Author(s):
Waters
Source:
Waters
Content Type:
Application Notes
Content Subtype:
Application Notebooks
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Waters’ latest innovations in sample preparation, LC, LC-MS, and informatics are designed to address the multi-faceted analytical needs of large molecule characterization – from the discovery and development of innovator biopharmaceuticals such as antibody drug conjugates (ADCs) to the successful commercialization of biosimilars/biobetters that satisfy international biotherapeutic drug regulatory requirements.

This application notebook is a compilation of 63 application notes discussing techniques and insights into biopharmaceutical analysis. The application notebook is organized by technique and covers:

  • SEC FOR CLIPS AND AGGREGATES
  • IEX FOR CHARGE VARIANTS
  • REVERSED-PHASE FOR PROTEIN SEPARATIONS
  • REVERSED-PHASE FOR PEPTIDE MAPPING
  • REVERSED-PHASE FOR AMINO ACID ANALYSIS
  • HILIC FOR RELEASED GLYCANS AND GLYCOPROTEINS
  • HIC FOR HYDROPHOBIC MOIETIES AND DRUG ANTIBODY RATIO (DAR)
  • MULTIDIMENSIONAL LIQUID CHROMATOGRAPHY (2D-LC)

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