Peptide and Protein Bioanalysis Application Notebook

Library Number:
APNT134830620
Part Number:
720005226EN
Author(s):
Waters
Source:
Waters
Content Type:
Application Notes
Content Subtype:
Application Notebooks
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Newly updated for 2017!

Peptides and Proteins are not Small Molecules; Why Treat Them the Same?

Whether you have been doing it for years or are just starting off, large molecule quantification creates a number of challenges for bioanalysts, including:

  • Sensitivity and specificity issues
  • Multiple charge states dilute signal
  • Complex fragmentation patterns
  • Endogenous proteins and peptides yield high background
  • And many, many more

Waters’ Peptide and Protein Bioanalysis Application Notebook (rev. November, 2016) outlines methods, inclusive of sample prep, separations, MS and informatics, helping scientists solve the most pressing and challenging analytical problems.

 

 
Highlights include:

  • 48 application notes written by more than 60 expert authors
  • 47 unique analytes - therapeutics and biomarkers
  • Covers tandem quads, HRMS (QTof), Tof MRM, microflow, informatics, and more
  • Peptides, proteins (surrogate peptide method & intact quantification), mAbs, ADCs, and others

For more content like this, visit our DMPK and Bioanalysis Knowledge Center.

Download the Peptide and Protein Bioanalysis Infographic here.

 


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