An Integrated LC-MS Platform for Multi-Attribute Monitoring of CQA’s of mAbs at the Subunit Level

Library Number:
APNT134963558
Part Number:
720006166EN
Author(s):
Nilini Ranbaduge, Henry Shion, Ying Qing Yu, and Weibin Chen
Source:
Waters
Content Type:
Application Notes
Content Subtype:
Application Notes
Related Products:
 
 
 
 
 

This application note demonstrates the use of LC-MS platform under compliant-ready software (UNIFI Scientific Information System) for Fc-core fucosylation and aglycosylation confirmation and monitoring their relative levels. Details on sample preparation, LC-MS setup and data processing are discussed in this application note.


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